None listed
Conditions
Brief summary
Cough commonly occurs after upper respiratory tract infection. The aim of the study is to determine whether early intervention for acute cough following upper respiratory tract infection (common cold) reduces the proportion of patients who develop chronic cough. The study involves a randomised control trial of intervention for acute cough involving 101 participants. Participants will undergo a baseline assessment and brief intervention. Follow-up visits to determine whether cough has persisted, reduced resolved will occur at 8, 12 and 26 weeks post-onset of cough.
Interventions
The cough suppression therapy involves advice regarding vocal hygiene particularly increasing hydration and reducing exposure to laryngeal irritants, avoid deliberate coughing and throat clearing using cough suppression strategies, reduce oral breathing to prevent irritation of the laryngeal mucosa, and reduce laryngeal strain if present. Patients will be given handouts of (1) vocal hygiene advice, and (2) the cough suppression exercises. Handouts will be developed for this study.
Therapy will b
The cough suppression therapy involves advice regarding vocal hygiene particularly increasing hydration and reducing exposure to laryngeal irritants, avoid deliberate coughing and throat clearing using cough suppression strategies, reduce oral breathing to prevent irritation of the laryngeal mucosa, and reduce laryngeal strain if present. Patients will be given handouts of (1) vocal hygiene advice, and (2) the cough suppression exercises. Handouts will be developed for this study. Therapy will be delivered by a qualified speech pathologist delivered in a single 1 hour session. The mode of delivery will be face to face at the Hunter Medical Research Institute, Newcastle, Australia, but telehealth appointments will be considered for patients who are unable to travel to the appointment.Intervention adherence will be measured at each follow up session and include estimation of whether the patient has implemented the strategies, demonstration of the strategies and implementation of the strategies to interrupt cough episodes. Intervention fidelity will be assessed after every participant for the first five participants and then if satisfactory, after every 10 participants.
Sponsors
John Hunter Hospital
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
• 18 years of age or older. • Cough between 3 and 6 weeks duration following upper respiratory tract infection • Cough severity visual analogue scale>39mm • Non-productive cough • Probable viral infection as defined by the Common Cold Questionnaire
Exclusion criteria
1. Primary diagnosis of history of cough secondary to lower airway disease 2. Haemoptysis 3. Productive cough of > 1 table spoon phlegm per day. 4. Cystic fibrosis 5. Bronchiectasis/bronchitis 6. Chronic obstructive pulmonary disease 7. Interstitial lung disease 8. Cognitive impairment, poor English language skills or significant untreated hearing impairment that prevents completion of data collection forms or understanding verbal instructions. 9. Inability to attend study visits. 10. Current smoker or smoker with >20 pack-year smoking history 11. Prominent dyspnoea, especially at rest or at night 12. History of unexplained weight loss 13. Chest pain 14. Current pneumonia 15. Medical concern regarding diagnosis
Outcome results
None listed