Analysis of Patient Outcomes following Platelet Rich Plasma Treatment for Joint Osteoarthritis

The observational study assessed the effectivenes of Platelet Rich Plasma (PRP) on Non-specific Ankle Pain and Knee Osteoarthritis. Pain levels was assessed from baseline (before PRP injection) to 2-3 months after final PRP treatment. This data was collected retrospectively. In order to prepare a single injection of PRP with supra-physiological platelet concentrations of up to three times normal, 17 mL of blood was collected from the patient’s cubital vein using a 21 G needle to a blood collection tube containing 1 mL of acid citrate, trisodium citrate-22.0g/L and citric acid-8.0g/L. Thus, two PRP tubes were produced, each containing 8.5 mL of blood. the buffy coat and plasma layers (PRP) were collected from the patient’s PRP tubes via an 18 G needle, into a single syringe. The volume of PRP in the syringe ranged from 7-8 mL. Knee- 7-8ml PRP injection, average of 4 treatments across 6 weeks Ankle joint- 7-8ml PRP injection, average of 4 treatments across 6 weeks Ankle Ligament- 5ml PRP injection, average of 3 treatments across 4 weeks The PRP treatment was administered by a number of general practitioners specialising in musculoskeletal conditions who have been trained in PRP treatment. Administeration was conducted at a number of medical clinics. Pain assessment was carried out 2-3 months following PRP administration.