Long-term Impact in Intensive Care Survivors of Coronavirus disease-19 (COVID-19)

Conditions

None listed

Brief summary

Long-term impact of COVID-19 on neurological, pulmonary, renal, liver function and health-related quality of life is unknown. We theorise that COVID-19 patients admitted to the ICU will have various degrees of organ dysfunctions up to 2 years post ICU discharge, which could result in an impaired quality of life and prolonged recovery. This is a multi-centre international prospective study in survivors of COVID-19, who required admission to the intensive care unit, to assess the health-related quality of life, the dynamics of organs dysfunction and recovery, cognitive outcome and pulmonary function.

Karin Wildi, Gianluigi Li Bassi, Adrian Barnett, Mauro Panigada, Sebastiano Maria Colombo et al. (24 authors)

Frontiers in Medicine2021-09-082 citations

10.3389/fmed.2021.738086

Interventions

Patients previously enrolled in ECMOCARD will be approached for informed consent for follow-up assessments up to 2 years. Following discharge from the hospital, recovery up to two years of the following aspects/functions will be assessed: - Health-related quality of life by answering questionnaires (taking approximately 1h at every follow-up visit) - Dynamics of organs dysfunction and recovery (blood draw, taking 5 minutes at every follow-up visit; ) - Pulmonary function tests (taking approximat

Patients previously enrolled in ECMOCARD will be approached for informed consent for follow-up assessments up to 2 years. Following discharge from the hospital, recovery up to two years of the following aspects/functions will be assessed: - Health-related quality of life by answering questionnaires (taking approximately 1h at every follow-up visit) - Dynamics of organs dysfunction and recovery (blood draw, taking 5 minutes at every follow-up visit; ) - Pulmonary function tests (taking approximately 2h at every follow-up visit) Follow-up assessments with the complete work-up will be at 3, 6, 12, 18 and 24 months.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

No

Inclusion criteria

Laboratory-confirmed COVID-19 infection by real-time PCR Written informed consent from the patient at the time of discharge from the ICU Previous enrolment into the ECMOCARD observational study Aged older or equal than 18 years Discharge from an intensive care unit

Exclusion criteria

Pregnancy at time of infection Patients unable to complete long-term follow-up, due to logistical problems Patient paralysed due to pre-existing neurological condition before being admitted to hospital for COVID-19 History of pulmonary resection Previous pulmonary transplant

Outcome results