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Post-Intensive Care Nutrition Status in Patients with COVID-19

Post-Intensive Care Nutrition Status in Patients with COVID-19

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12620000602921
Enrollment
103
Registered
2020-05-25
Start date
2020-05-01
Completion date
2021-03-31
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Patients with COVID-19 admitted to intensive care are at high risk of nutritional concerns such as high fevers, increased energy utilisation, impaired glucose utilisation, and increased catabolic state and protein breakdown. Post-ICU there may be significant effects on appetite, taste sensations and direct gastrointestinal affects resulting in diarrhoea, nausea, and vomiting. While no data exist on nutritional intake post-ICU in patients diagnosed with COVID-19, significant nutritional deficits in other cohorts of ICU survivors have been demonstrated. Further, similar conditions, such as Acute Respiratory Distress Syndrome, are associated with substantial acute weight loss during hospitalisation, with long-term muscle weakness and functional impairments. If they survive, patients with COVID-19 are likely to have prolonged recovery and stay in hospital for a significant length of time. Coupled with stretched healthcare resources, this cohort of patients may be particularly susceptible to nutritional deficits, declining nutritional status, and poor functional recovery. Given there is limited available data to guide the optimal nutritional management of patients with COVID-19, we aim to quantify nutrition intake and process in survivors of COVID-19 after ICU discharge. Therefore, we are conducting a multi-centre observational study, across participating sites in Australia. As this is a descriptive study the following (but not limited to) outcomes are of interest: - Nutrition service delivery - Nutrition provision at the patient level - Nutrition information on patients with COVID-19

Interventions

As an observational study, data will be collected with the aim of quantifying the effect of the COVID-19 respiratory pandemic on nutrition intake, processes and dietetic resourcing in patients admitted to intensive care in Australia that survive to the ward. Nutrition data will be collected for patients once they are discharged to an acute hospital ward for every 7 days up to hospital discharge or day 28. Data will be collected retrospectively for patients' ICU admission, including patient de

As an observational study, data will be collected with the aim of quantifying the effect of the COVID-19 respiratory pandemic on nutrition intake, processes and dietetic resourcing in patients admitted to intensive care in Australia that survive to the ward. Nutrition data will be collected for patients once they are discharged to an acute hospital ward for every 7 days up to hospital discharge or day 28. Data will be collected retrospectively for patients' ICU admission, including patient demographics and nutrition data. Therefore, data may be collected retrospectively for patients who were admitted and enrolled into the SPRINT-SARI study, the date of which may be prior to this trial registration and study commencement.

Sponsors

The Australian and New Zealand Intensive Care Research Centre
Lead SponsorOther Collaborative groups

Eligibility

Sex/Gender
All
Age
16 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Only patients included in Short Period Incidence Study of Severe Acute Respiratory Infection (SPRINT-SARI) ( https://www.anzics.com.au/current-active-endorsed-research/sprint-sari/) will be included in this nutrition study. Patients admitted to the participating sites and enrolled in SPRINT-SARI will be screened at ICU discharge for eligibility for inclusion in the study. All investigators involved in screening and recruitment are employed by the corresponding sites and will have access to identifiable patient information purely for the purpose of study eligibility and study data collection. The SPRINT-SARI patient identification number (PIN) will be recorded as a case report form data point to allow for data linkage at a later date. SPRINT-SARI will enrol all patients admitted to hospital with suspected or proven acute novel Coronavirus (nCoV) infection as main cause for admission. The study population for SPRINT-SARI, as follows: All patients newly admitted to participating hospitals, of any age, presenting with SARI during the study period. Patients will be eligible for the study if the patient meets the case definition for SARI. A suspected or proven acute respiratory infection requiring new inpatient admission with onset within the past 14 days. With one or more of the inclusion criteria. Inclusion Criteria: -A history of feverishness or measured fever of greater than of equal to 38 deg C; -Cough; -Dyspnoea (shortness of breath) OR Tachypnoea. Additional inclusion for this study: - COVID-19 positive diagnosis - Admitted to an Intensive Care Unit (ICU)

Exclusion criteria

- Admitted to an Intensive Care Unit (ICU) for <24 hours - Not discharged to an acute ward post an ICU admission - For palliative care on ICU discharge

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026