Rapid eye movement (REM) related obstructive sleep apnoea (OSA) and continuous positive airway pressure (CPAP) treatment

1. Continuous positive airway pressure (CPAP) treatment: a CPAP titration study undertaken at Baseline to prevent snoring and return obstructive events to the normal range (standard laboratory protocol). The CPAP titration study will take place in the Sleep Laboratory at Westmead Hospital. Anthropometric data will also be collected including age, gender, height, weight, BMI, blood pressure and neck circumference. Psychomotor Vigilance Test will be performed prior to sleep and repeated within 30 minutes of wakening. The CPAP equipment will be given to the participant on the morning of CPAP titration visit (Baseline visit) to take home and commence therapy. The study coordinator will contact the participants via telephone on a monthly basis to monitor CPAP compliance. CPAP treatment period will run for 12 months with loan mask and CPAP machine provided by Sleep Laboratory from loan pool. 2. Questionnaires and tests will be administered at 1, 3, 6 and 12 months and include Epworth Sleepiness Scale (ESS), Functional Outcomes of Sleep Questionnaire (FOSQ), depression anxiety and stress score (DASS-21), and Psychomotor Vigilance Test (PVT – test of neuropsychological function). Anthropometric data (weight, BMI, blood pressure and neck circumference), CPAP compliance and adverse events will be reviewed and collected. The participant will attend Westmead Hospital for each visit and the study coordinator will administer the interventions described above.