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Effect of hyperoxia in pediatric patient via oxygen reserve index monitoring

Prevention of harmfull effect of hyperoxia with new monitorization method : ORI (oxygen reserve index )

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12620000553976
Enrollment
20
Registered
2020-05-11
Start date
2020-07-09
Completion date
Unknown
Last updated
2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Our primary goal in this prospective study was to compare the oxygen reserve index and arterial oxygen pressure in patients undergoing preoxygenation with inspiratory oxygen at different concentrations. 2-24 months old children who will undergo craniocinocytosis surgery will be included in the study. Patients will be preoxygenated using 100% inspiratory oxygen concentration and air. During this process, SpO2 and ORI values of the patients will be recorded continuously .The ORI values will be monitored continuously with the Rainbow1 20L probe (Masimo, Irvine, CA) connected to the Radical-7 Pulse CO-Oximeter. After induction of anesthesia, the probe will be placed on the ring finger of the non dominant and the arterial monitoring is not performed hand , according to the recommendations of the manufacturer and wrapped to prevent any environmental factors. Preoxygenation and tracheal intubation will be carried out by the same anesthesiologist. Invasive artery monitorization and central venous pressure, catheterizations will be performed.

Interventions

2-24 months old children who will undergo craniocinocytosis surgery will be included in the study. Patients will be preoxygenated using 100% inspiratory oxygen concentration + air. Patients will be given inhalation anesthesia with 2% sevoflurane.In induction, after intubation, 60-, 120-, 180- and 240-minute arterial blood gas samples will be taken to determine PaO2.During this process, SpO2 and Oxygen reserve index (ORI) values of the patients will be recorded continuously by anaeshesiologist v

2-24 months old children who will undergo craniocinocytosis surgery will be included in the study. Patients will be preoxygenated using 100% inspiratory oxygen concentration + air. Patients will be given inhalation anesthesia with 2% sevoflurane.In induction, after intubation, 60-, 120-, 180- and 240-minute arterial blood gas samples will be taken to determine PaO2.During this process, SpO2 and Oxygen reserve index (ORI) values of the patients will be recorded continuously by anaeshesiologist via memorystick.

Sponsors

Marmara University Medical Faculty
Lead SponsorUniversity

Eligibility

Sex/Gender
All
Age
2 Months to 24 Months
Healthy volunteers
No

Inclusion criteria

20 children who will undergo craniocinocytosis surgery, ASA I-II, 2-24 months of age and written informed consent from their families or legal officers will be included in the study.

Exclusion criteria

Children with congenital or traumatic extremity pathology, with a history of allergy to the sensor material and body weight of less than 3 kg, patients with rectal abnormalities, thus contraindicated for rectal temperature probe placement, patients undergoing emergency surgery, or known heart failure or hypertension children with cardiac or vascular disease will be excluded from the study.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026