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Investigating Complications in Men who have Undergone Surgical Reconstruction of the Urethra using Oral Grafts

Evaluating Donor Site Complications after Buccal Mucosal Grafting for Urethroplasty

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12620000521921
Enrollment
100
Registered
2020-04-28
Start date
2020-05-01
Completion date
Unknown
Last updated
2020-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

1. Background Urethral strictures are a common cause of urinary issues for men worldwide. Repair of the urethra with a tissue graft taken from inside the cheek is currently the best treatment for long urethral strictures. Whilst the use of an oral graft to repair urethral strictures is well studied, there has been less research into mouth problems (e.g. pain, infection) after the graft is taken. 2. Aims This study aims to determine the rate of post-operative mouth problems in men who had an oral graft taken from inside their cheek and used to repair their urethral stricture. This study will also investigate if certain patient's features (e.g. age, medical conditions) or operative details (e.g. size of oral graft, length of urethral stricture) are more likely to result in complications after the surgery. 3. Hypothesis Patients who have an oral graft surgically removed are at risk of developing mouth problems. Some patient features or operative details may increase the likelihood of complications.

Interventions

The primary aim of this retrospective observational study is to determine the occurrence of post-operative complications at the BMG donor site in patients who have undergone BMG harvesting for urethroplasty at Toowoomba Hospital and St Vincent’s Private Hospital between 1st January 2017 and 31st December 2019. Secondarily, this study will evaluate the demographic, medical and operative characteristics of patients who have undergone BMG harvesting for urethroplasty at Toowoomba Hospital and St

The primary aim of this retrospective observational study is to determine the occurrence of post-operative complications at the BMG donor site in patients who have undergone BMG harvesting for urethroplasty at Toowoomba Hospital and St Vincent’s Private Hospital between 1st January 2017 and 31st December 2019. Secondarily, this study will evaluate the demographic, medical and operative characteristics of patients who have undergone BMG harvesting for urethroplasty at Toowoomba Hospital and St Vincent’s Private Hospital between 1st January 2017 and 31st December 2019. All data will be collected from the pre-existing hospital records of these patients.

Sponsors

Dr Devang Desai
Lead SponsorIndividual

Eligibility

Sex/Gender
Male
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

(i) Males (> 18 years of age) (ii) Patients who have undergone urethroplasty surgeries at Toowoomba Hospital and St Vincent’s Private Hospital (iii) Procedures performed between the 1st January 2017 and the 31st December 2019.

Exclusion criteria

Males under the age of 18

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026