None listed
Conditions
Brief summary
Title: Type1Screen: Diabetes autoantibody screening to identify individuals at risk for type 1 diabetes Objectives: 1) To identify individuals who have diabetes autoantibodies 2) To support antibody-positive individuals through a national network of diabetes centres and to perform metabolic testing to determine their risk of developing type 1 diabetes
Interventions
The Type1Screen study provides antibody screening for individuals aged 2-30 years old; in particular screening is for IA2, GAD, ZnT8 and insulin antibodies.
For participants under the age of 18, repeat antibody screening will be offered every 5 years until adulthood (age 18 years).
Antibody screening is not part of routine clinical care and is being offered to family members who wish to know their risk of developing type 1 diabetes and, if the test is positive, wish to consider joining inter
The Type1Screen study provides antibody screening for individuals aged 2-30 years old; in particular screening is for IA2, GAD, ZnT8 and insulin antibodies. For participants under the age of 18, repeat antibody screening will be offered every 5 years until adulthood (age 18 years). Antibody screening is not part of routine clinical care and is being offered to family members who wish to know their risk of developing type 1 diabetes and, if the test is positive, wish to consider joining intervention trials that aim to delay or prevent progression to insulin dependence. Participation involves reading and signing a consent form (20 minutes), completing an online survey (10 minutes) and presenting to a community blood collection centre for a blood test (30 minutes). Alternatively, where additional validated assays for antibodies become available, instead of a community blood collection, participation may involve a home test kit with instructions to collect saliva and blood prick samples (30mins).
Sponsors
Melbourne Health
Eligibility
Sex/Gender
All
Age
2 Years to 100 Years
Healthy volunteers
Yes
Inclusion criteria
1. People aged over 2 years AND 2. Live in Australia AND 3. Have a relative diagnosed with type 1 diabetes OR have previously had a positive antibody screen 4. Participant or guardian willing and competent to provide informed consent.
Exclusion criteria
1. Someone with a diagnosis of diabetes (other than gestational diabetes which resolved after the baby was born) 2. Someone who is unable to give a blood test 3. A participant, or their legal guardian, who is unable to give consent to participate
Outcome results
None listed