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Study evaluating Front-line health care workers serial blood COVID-19 antibody results in relation to symptom presentation

Prospective study evaluating the proportion of SARS-CoV-2 (COVID-19) antibody seroconversion in frontline health care workers on serial evaluation in comparison to symptom presentation.

Status
Withdrawn
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12620000493943
Acronym
COVIDCONVERT
Enrollment
50
Registered
2020-04-20
Start date
Unknown
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The study will review SARS-CoV-2 IgG, IgA and IgM antibodies in front-line health care workers every month for six months in comparison to symptom presentation.

Interventions

Front-line Healthcare Workers Participants will have serial (monthly) SARS-CoV-2 IgG, IgA and IgM antibody serum sample analysed for six months and Coronavirus symptom data collection. Front-line health care worker participants will be requested to records symptoms in a diary each day. This will be reviewed monthly by a research staff member.Front-line health care worker participants who develop symptoms consistent with COVID-19 will be assessed at the Coronavirus clinic as per standard practice

Front-line Healthcare Workers Participants will have serial (monthly) SARS-CoV-2 IgG, IgA and IgM antibody serum sample analysed for six months and Coronavirus symptom data collection. Front-line health care worker participants will be requested to records symptoms in a diary each day. This will be reviewed monthly by a research staff member.Front-line health care worker participants who develop symptoms consistent with COVID-19 will be assessed at the Coronavirus clinic as per standard practice. Any nasopharyngeal swabs collected and tested will be compared to the symptoms diary and serology results. Upon completion of 6 months, no further follow up is required.

Sponsors

Albury Wodonga Health
Lead SponsorHospital

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

• Participants aged 18 years or over • Participants who are front-line health care workers that may have cared for SARS-CoV-2 positive patients and/or been involved in testing suspected SARS-CoV-2 patients and/or work in a high-risk setting. High-risk setting is defined as the Emergency Department, Intensive Care, Medical wards caring for patients with COVID-19 or dialysis unit • Participants must be accessible for follow up testing • Able to read, write and understand English Participant Information and Consent Form • Signed Participant Information and Consent Form

Exclusion criteria

• Medical or psychiatric condition or occupational responsibilities that may preclude compliance with the protocol • Research study personnel as identified in this Protocol

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026