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Study evaluating Coronavirus (COVID-19) nasal/oral swab results compared to blood antibody results in COVID-19 clinic patients.

Retrospective and prospective study evaluating the sensitivity of upper respiratory swabs for SARS-CoV-2(COVID-19) NAT by determining the prevalence of SARS-CoV-2 antibody seroconversion following an initial negative swab in participants that have presented to the COVID-19 clinic

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12620000487910
Acronym
COVIDCONVERT
Enrollment
103
Registered
2020-04-20
Start date
2020-04-07
Completion date
2020-06-19
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study will compare standard of care nasopharyngeal swab NAT results to the presence of SARS-CoV-2 IgG, IgA and IgM antibodies approximately 14 days after initial onset of symptoms in intermediate/high risk participants presenting to the Albury Wodonga Health Coronavirus Clinic.

Interventions

Coronovirus Screening Clinic Participants Participants have SARS-CoV-2 IgG, IgA and IgM antibody serum sample analysed approximately 14 days after developing Coronavirus symptoms. Upon completion of blood sampling, no further follow up is required. Data to be collected for the study will include general patient demographics, medical history, baseline SARS-CoV-2 NAT pathology results, SARS-CoV-2 Risk assessment and symptom assessment.

Sponsors

Albury Wodonga Health
Lead SponsorHospital

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

• Participants aged 18 years or over • Participants who have attended Albury-Wodonga Health Coronavirus Screening clinic and have had a NP swab collected for SARS-CoV-2 NAT .• Both participants that have returned a negative or a positive swab will be included in the study. • Participants must be accessible for follow up testing • Able to read, write and understand English Participant Information and Consent Form • Signed Participant Information and Consent Form

Exclusion criteria

• Participants under 18 years of age • Unwilling to be contacted for follow up testing • Medical or psychiatric condition or occupational responsibilities that may preclude compliance with the protocol • Research study personnel as identified in this Protocol

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 12, 2026