None listed
Conditions
Brief summary
Prior research has suggested that in adult patients requiring mechanical ventilation for hypoxic respiratory failure, that airway pressure release ventilation (APRV) is associated with a mortality benefit and improved oxygenation when compared to conventional ventilation strategies. The Western Australian Intensive Care clinical community has extensive experience with APRV, including during the H1N1 epidemic. The aim of this observational study is to record the outcomes for mechanically ventilated patients with COVID-19, with the expectation that a significant proportion of WA intensive care clinicians will choose APRV. Analysis will compare APRV with non-APRV ventilation modes.
Interventions
Airway pressure release ventilation has traditionally been used as a rescue mode of mechanical ventilation for patients with ARDS (acute respiratory distress syndrome), however it may also be beneficial early on in ARDS. It helps with recruitment (opening up) of lungs by having a continuous high level of positive pressure and timed pressure release. Spontaneous breathing is still possible.
The mode of ventilation provided to patients is chosen at the discretion of the treating clinician. Mode
Airway pressure release ventilation has traditionally been used as a rescue mode of mechanical ventilation for patients with ARDS (acute respiratory distress syndrome), however it may also be beneficial early on in ARDS. It helps with recruitment (opening up) of lungs by having a continuous high level of positive pressure and timed pressure release. Spontaneous breathing is still possible. The mode of ventilation provided to patients is chosen at the discretion of the treating clinician. Mode of mechanical ventilation received by intubated patients in ICU is being observed from intubation until extubated.
Sponsors
Sir Charles Gairdner Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Mechanically ventilated COVID-19 positive Admitted to Intensive Care Unit in participating Western Australian ICU
Exclusion criteria
None
Outcome results
None listed