Skip to content

Evaluation of the Effectiveness of Noninvasive PVI (Pleth Variability Index) Monitorization on Geriatric Treatment and Intraoperative Hemodynamics in Geriatric Surgery

Evaluation of the Effectiveness of Noninvasive PVI (Pleth Variability Index) Monitorization on Geriatric Treatment and Intraoperative Hemodynamics in Geriatric Surgery

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12620000419965
Enrollment
100
Registered
2020-03-30
Start date
2019-04-08
Completion date
2019-09-02
Last updated
2021-06-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

It is often not possible to determine the reserve of organ functions in geriatric patients undergoing surgical intervention. Therefore; In this age group, it is of utmost importance to apply the ideal amount of fluid and / or blood replacement during intraoperative period in order to prevent possible organ damage. The aim of this study was to determine the effect of Pleth Variability Index (Pleth) Index monitoring on intraoperative volume replacement in geriatric patients undergoing surgical intervention.

Interventions

It is often not possible to determine the reserve of organ functions in geriatric patients undergoing surgical intervention. Therefore; In this age group, it is very important to apply the ideal amount of fluid and / or blood replacement during intraoperative period in order to prevent possible organ damage. The use of Perioperative Targeted Fluid Therapy Technologies helps the anesthesiologist closely monitor the patient and establish a delicate balance between benefit and risk. Plethysmatic va

It is often not possible to determine the reserve of organ functions in geriatric patients undergoing surgical intervention. Therefore; In this age group, it is very important to apply the ideal amount of fluid and / or blood replacement during intraoperative period in order to prevent possible organ damage. The use of Perioperative Targeted Fluid Therapy Technologies helps the anesthesiologist closely monitor the patient and establish a delicate balance between benefit and risk. Plethysmatic variability index monitoring (PVI-Pleth Variability Index) is a non-invasive, automatic and continuous monitor that shows the fluid response of the patients and is one of the easily applicable and easily interpretable monitoring methods. It has been shown that intraoperative hypotension and fluid requirement can be predicted by PVI monitoring.The aim of this study was to determine the effect of Pleth Variability Index (Pleth) Index monitoring on intraoperative volume replacement in geriatric patients undergoing surgical intervention. MATERIAL AND METHOD: After approval of the ethics committee and written consent of the patient; 100 patients over the age of 65 (ASA class 2-3) undergoing elective surgery were included in the study. In addition to standard monitoring, PVI monitoring was performed in all patients. After randomization with closed envelope method, intraoperative fluid and blood product replacement was performed in half of the patients based on PVI data (threshold value 13%) (Group PVI); In the other half, PVI values were blinded and applied by conventional methods (Group K). Hemodynamic values, fluid and blood product amount, vasopressor requirements were recorded at 15-minute intervals and t, Mann-Whitney U or chi-square tests were evaluated. Administers the intervention by anaesthesiologists.

Sponsors

meliha orhon ergun
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Primary purpose
Prevention

Eligibility

Sex/Gender
All
Age
65 Years to No maximum
Healthy volunteers
No

Inclusion criteria

65 years and older, all patients who do not meet the exclusion criteria will be included in the study.

Exclusion criteria

Patients with severe cardiac arrhythmia and peripheral arterial disease, an ejection fraction of less than 30%, mechanical ventilation and a pulmonary pathology that prevents breathing of more than 6 ml / kg and liver and kidney dysfunction will be excluded.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026