Hypnotherapy for patients with Crohn’s disease

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Crohn's disease (CD) is a type of inflammatory bowel disease (IBD) - a chronic gastrointestinal disorder - associated with high disease burden and psychological comorbidity. Gut-directed hypnotherapy may be a type of psychological intervention useful for people with CD, as it has been well-researched as a treatment for functional gastrointestinal (GI) disorders (particularly Irritable Bowel Syndrome) with considerable evidence for reduced symptom burden and improved mental health. In the IBD literature however, hypnotherapy has received very little attention, with most research comprising case studies, and no previous trials conducted specifically with CD patients. This pilot trial will investigate the feasibility of conducting a future randomised controlled trial (RCT) of virtual adjunctive gut-directed hypnotherapy for patients with CD. Participants will be randomised to one of two groups: Control group will receive medical treatment as usual (TAU); Intervention group will receive usual medical therapy plus adjunctive gut-directed hypnotherapy delivered via telehealth. Primary outcomes are study feasibility endpoints (e.g. recruitment rates, intervention completion and acceptability, and acceptability of study procedures). Participants will complete assessments at five time-points (in line with pre-treatment, post-treatment, and follow-up three-, six- and 12 months post-treatment) to measure potential changes in disease activity, mental health and quality of life (secondary measures). This research will be a collaborative project between the Central Adelaide Local Health Network and Deakin University, and will contribute to the PhD of the Principal Investigator (PI: TL).

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