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The effects of the education program and other factors on the number of sedative medications that older people with dementia regularly consume.

Effective approaches and interventions to reduce the inappropriate prescription of psychotropic medications (antipsychotic and benzodiazepine) in people living with dementia.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12620000268943
Enrollment
56
Registered
2020-02-28
Start date
2019-11-25
Completion date
2021-03-10
Last updated
2024-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The aims of this study are as follows: 1. To determine whether an education program directed at nurses, pharmacists and professional care staff will reduce the use of sedative medications in older people with dementia living in Residential Aged Care Facilities (RACF). 2. To determine the effects of the education program and other factors on the number of sedative medications that older people with dementia regularly consume. This project is aimed to reduce the use of antipsychotics and benzodiazepines among residents with dementia through the education program. These medications were associated with a significant increase in adverse events and an increased risk of mortality. Previous studies have suggested that these medications can also affect the cognitive state among older adults with dementia. Benzodiazepine use has been associated with accelerated cognitive decline and limited benefits. Antipsychotic medications have also been associated with considerable cognitive adverse effects in people with dementia. Degeneration of cognitive function and mood often reduces quality of life amongst people living with dementia. Therefore, it is important to investigate the effect of these medications on cognitive state and the quality of life of dementia residents .

Interventions

Educational intervention • A multi-strategic, inter-disciplinary intervention (25 nursing homes) will be undertaken to reduce and promote the appropriate use of psychotropics, anti psychotics and benzodiazepines in Residential Aged Care Facilities (RACFs). -The Dementia Training Australia team (DTA) will conduct this intervention at (RACFs). They will provide online training components of the medication consultancy course for RACF staff. This course will be conducted twice and will take approxim

Educational intervention • A multi-strategic, inter-disciplinary intervention (25 nursing homes) will be undertaken to reduce and promote the appropriate use of psychotropics, anti psychotics and benzodiazepines in Residential Aged Care Facilities (RACFs). -The Dementia Training Australia team (DTA) will conduct this intervention at (RACFs). They will provide online training components of the medication consultancy course for RACF staff. This course will be conducted twice and will take approximately 30 minutes. The other part of the medication consultancy training is regular, short educational meetings with change champion groups in the RACFs. DTA will conduct 30-minute meetings (video conferences), group size up to 6 staff members (preferably the Change Champion/s) approx. every 2-4 weeks and there are approx. 8 meetings to complete throughout the Medication Management Consultancy (MMC) which usually run for approx. 6 months. If sites are located in WA, our aim to visit them face to face for the initial meeting and last. DTA team use the OAPQ (knowledge quiz about at T1 and T2), the antipsychotic audit (at T1 and T2) and three DTA surveys: • Survey 1 – provided to any staff member who completed the one-hour online medication management course during the MMC. This is a knowledge translation-type survey, specifically asking staff about the one-hour online course and how this might have changed/influenced their practice. • Survey 2 - provided to the Action Group and Change Champion/s only to mark the end of the MMC. This is a knowledge translation-type survey, specifically asking staff about the MMC as a whole and how this might have changed/influenced their practice. • Survey 3 – provided to the Action Group and Change Champion/s only 3-6 months post-MMC. This is a knowledge translation-type survey, specifically asking staff about the MMC as a whole and how this might have changed/influenced their practice 3-6 months post-MMC. The researchers will be involved by following the process and making sure the data is collected to ensure fidelity and monitor data collection. • A comprehensive pragmatic cluster randomised trial will be conducted in 11 RACFs – Western Australia and the estimated number of residents within these facilities is approximately 409-439 residents. This study aims to evaluate the pattern of use of psychotropic drugs by residents of RACFs before and after an educational intervention program. The educational intervention will be implemented by DTA staff over 3 to 6 months. All the clusters will provide baseline data on entry into the study. • Sub-study. (n= 56) Quality of Life (QoL) Measures: QoL was assessed by the self-reported Quality of Life in Alzheimer’s Disease (QoL-AD), neuropsychiatric symptoms and staff distress by Neuropsychiatric Inventory–Questionnaire version (NPI-Q), cognition by Standardised Mini-Mental State Examination (SMMSE) and activity of daily living assessment by Bristol Activity of Daily Living Scale (BADLS). Medication data were obtained from residents’ medication charts. Repeated assessments of all the above variables were performed at 6 and 12 months. All participants are voluntary, and they can withdraw at any time without any reason. The researcher will first arrange consent with the residential aged care facility (RACF), then participants will be either consented to be part of the study or a proxy (a close family member) will provide consent on their behalf if the participant has moderate to severe cognitive impairment and is unable to provide consent. • Firstly, the recruited nursing home will send an email to the residents’ relatives/families to inform them about the research project. Those persons/families who indicate an interest will be contacted by the researcher who will provide them with the project’s Information Sheet and consent form to participate. The participant will also consent, if they have capacity, or if they do not have capacity to consent, they will provide assent. In those participants who lack capacity to consent, consent will be provided by a proxy decision maker (a close family member, next of kin). •Participants who agreed to participate in this research, will complete QoL survey. Then, the carer will complete the Neuropsychiatric Inventory (NPI), and Bristol Activities of Daily Living Scale for the participants. This survey will be administered at the baseline, 3-6 months post the intervention. •The de- Identifiable data (anonymous) will be also collected from RACFs regarding (psychotropics, antipsychotics and benzodiazepines) at baseline, 6 months post intervention and follow-up at 12 months

Sponsors

Dementia Training Australia (WA)
Lead SponsorGovernment body

Study design

Allocation
Randomised controlled trial
Intervention model
Other
Primary purpose
Educational / counselling / training
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
20 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

-Diagnosis of dementia in RACFs will be used to select participants for this. Study participants will be identified based on a recorded medical dementia diagnosis, or a diagnosis that will be evaluated during the study. Dementia will be diagnosed using ICD 10 criteria. -Educational intervention: Staff members (nurses and personal care assistances working in RACF etc.) will be recruited in the study.

Exclusion criteria

Residents with severe dementia, unable to give verbal answers

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026