None listed
Conditions
Brief summary
Colonoscopy is one of the most common day case procedures allover the world. Propofol has been the gold standard drug used for sedation and anesthesia for such cases. In our trial we will examine the efficacy of using dexmedetomidine and lidocaine infusion as an alternative to propofol infusion in such cases
Interventions
Patients scheduled for colonoscopy will be devided into two groups to receive either sedation by propofol infusion or by combined dexmedetomidine and lidocaine.
(A) propofol infusion at dose 25-75 ug/kg/min, Lidocaine infusion 1-2 mg/kg/hour and Dexmedetomidine infusion 0.2-0.5 ug/kg/min, all the infusions will start just before the beginning of the procedure.
(B) Drugs will be administered all-through the duration of the procedure
(C) Drugs will be administered by intravenous infusion
(D) Th
Patients scheduled for colonoscopy will be devided into two groups to receive either sedation by propofol infusion or by combined dexmedetomidine and lidocaine. (A) propofol infusion at dose 25-75 ug/kg/min, Lidocaine infusion 1-2 mg/kg/hour and Dexmedetomidine infusion 0.2-0.5 ug/kg/min, all the infusions will start just before the beginning of the procedure. (B) Drugs will be administered all-through the duration of the procedure (C) Drugs will be administered by intravenous infusion (D) The primary anesthesiologist ( the anesthesiologist who planned the methodology ) will be responsible for administration. (E) The group who will receive lidocaine and Dexmedetomidine will be the intervention group
Sponsors
NMC Royal Hospital
Study design
Allocation
Randomised controlled trial
Primary purpose
Treatment
Eligibility
Sex/Gender
All
Age
19 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
All adult ASA I and II patients admitted for elective colonoscopy
Exclusion criteria
Patients with bradycardia (heart rate < 55/min). Patients with known allergy to. lidocaine or dexemedotimidine
Outcome results
None listed