None listed
Conditions
Brief summary
In this study we propose to investigate the effects of applying TMS using a novel individualised site targeting methodology with a behavioural outcome for the purpose of enhancing cognitive flexibility.
Interventions
A first experimental session will be conducted to determine the 'optimal' and 'suboptimal' sites for transcranial magnetic stimulation (TMS) using a cognitive task. TMS involves the administration of strong, high frequency magnetic pulses to the brain. Participants will be required to complete a cognitive task while receiving TMS to different stimulation sites. The 'optimal' site is that where the largest effect of TMS on performance occurs, and the 'suboptimal' site is that where the smallest e
A first experimental session will be conducted to determine the 'optimal' and 'suboptimal' sites for transcranial magnetic stimulation (TMS) using a cognitive task. TMS involves the administration of strong, high frequency magnetic pulses to the brain. Participants will be required to complete a cognitive task while receiving TMS to different stimulation sites. The 'optimal' site is that where the largest effect of TMS on performance occurs, and the 'suboptimal' site is that where the smallest effect of TMS occurs. The duration of this session is approximately 1 hr. This session will occur approximately 1 week prior to the first intervention session. Arm 1: TMS administered by a university student to an optimised, individualised stimulation site for approximately 3 min at the Black Dog Institute. TMS will involve the administration of strong, high frequency magnetic pulses to the brain. Arm 2: TMS administered by a university student to a suboptimal, individualised stimulation site for approximately 3 min at the Black Dog Institute. TMS will involve the administration of strong, high frequency magnetic pulses to the brain. Arm 1 and Arm 2 will be conducted at least 2 days apart.
Sponsors
UNSW
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject)
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
Healthy, right handed, not taking any concurrent medications which may affect TMS effects (e.g., benzodiazepines), free from any neurological or psychiatric disorder, no recent head injury, no history of seizure or stroke, and no current history of drug or alcohol abuse or dependence.
Exclusion criteria
History of any psychiatric or neurological illness, seizure, stroke, any serious medical conditions, or current pregnancy
Outcome results
None listed