None listed
Conditions
Brief summary
There is a need to identify WHY fall and fracture risk is increased among Aboriginal and Torres Strait Islander (Indigenous) Australians. Indigenous Australians have a substantially greater fracture risk: Indigenous men are 50% and women are 26%, more likely to experience a hip fracture vs non-Indigenous Australians. Hip fractures occur at a much younger age in Indigenous vs non-Indigenous Australians (men:65 vs 81yrs; women:74 vs 83yrs). Fall-related injuries in Indigenous Australians increased by an average of 10%/year, while the average increase in non-Indigenous Australians was 4.3%/year. Findings from this study will identify why falls and minimal trauma fractures are higher among Indigenous adults. Data collected will enable us to determine the age of osteoporosis (bone fragility) and sarcopenia (decreased muscle function) onset, whether these are different to non-Indigenous Australians, and the best “window” for osteoporosis and sarcopenia screening and prevention strategies. Currently, there is no reference database for DXA-derived areal bone mineral density (aBMD) in Indigenous Australians, which may result in underestimation of fracture risk in this population. Data collected will be compiled into a reference database for Indigenous Australians as a starting point to collect data from Indigenous Australians in other geographic regions, with the aim of improving fracture risk prediction. Together, these data will enable health care professionals to improve screening, diagnosis and treatment of osteoporosis.
Interventions
This is a prospective longitudinal observational study, recruiting Aboriginal and Torres Strait Islander Australians (Indigenous Australians) residing in the Melbourne region (Australia), with a total of 298 adults. Stratified sampling by age and sex will be used to ensure equal distribution of men and women across the four age-bands, namely 35-44, 45-54, 55-64, 65+ years. Recruitment will include: referrals from clinicians at Monash Health; emails and speaking engagements with community groups,
This is a prospective longitudinal observational study, recruiting Aboriginal and Torres Strait Islander Australians (Indigenous Australians) residing in the Melbourne region (Australia), with a total of 298 adults. Stratified sampling by age and sex will be used to ensure equal distribution of men and women across the four age-bands, namely 35-44, 45-54, 55-64, 65+ years. Recruitment will include: referrals from clinicians at Monash Health; emails and speaking engagements with community groups, including yarning circles, Elders social gatherings, and various committee meetings, by invitation and support from Monash University Elder in residence; advertising posters displayed at various Victorian Aboriginal Health Services and Aboriginal Gathering Places; networking and communicating with various Indigenous communities with the support of the Monash Indigenous Engagement Unit and the Bunurong Health Service. Participants will come into Monash Medical Centre for a study visit at baseline, follow-up 1 and follow-up 2. The interval between study visits will be 12-15 months. Data collected will include: - Questionnaires: demographics, reproductive history, sarcopenia and quality of life (SarQoL), Osteoporosis Knowledge Assessment Tool, Osteoporosis Health Belief Scale, and the International Physical Activity Questionnaire (IPAQ) - Short Form. - Anthropometry: height, weight, sidedness, blood pressure and pulse. - Bloods: clinical indicators of diabetes, cardiovascular disease and chronic kidney disease will be measured. - Food frequency questionnaire (FFQ) from the Victorian Cancer Council (DQES) - Bone health: dual energy x-ray absorptiometry (DXA), high resolution peripheral quantitative computed tomography (HR-pQCT) and pQCT - Body composition: DXA and pQCT - Muscle strength: hand grip strength, jumping mechanography and short physical performance battery (SPPB) Each study visit will take approximately 1.5-2hrs.
Sponsors
Monash University
Eligibility
Sex/Gender
All
Age
35 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
Inclusion criteria for eligibility includes the participant: - To identify as Aboriginal or Torres Strait Islander - Aged 35 years and over - Body weight less than 160 kg (maximum rating of imaging machines)
Exclusion criteria
The exclusion criteria include: - Pregnant women - Lactating women - Breastfeeding in the last 6 months
Outcome results
None listed