None listed
Conditions
Brief summary
The IDEAL-EX Project will compare the effect of combined high-intensity interval training (HIIT) and progressive resistance training (PRT) against HIIT alone for improving cardiometabolic risk factors in older adults. Both groups will attend UNSW and receive supervised exercise sessions, 3 non-consecutive days a week over 12 weeks. The HIIT+PRT group will perform 20 minutes of HIIT followed by 4 high-intensity PRT exercises. The HIIT group will perform 20 minutes of HIIT only and be instructed to avoid PRT during the intervention. Study Importance: Investigating whether a novel, combined high-intensity aerobic and resistance training exercise program is safe, feasible and more efficacious at improving muscle strength than HIIT alone in an older adult population with moderate risk of cardiometabolic disease. We aim to build on the emerging literature that high-intensity aerobic and resistance exercise can be safe as well as effective in these individuals. The IDEAL-EX Project may also help to determine whether HIIT+PRT can deliver superior improvements to cardiorespiratory fitness and cardiovascular risk factors (such as blood pressure, cholesterol levels and blood glucose levels) compared to HIIT alone for older adults. The results will aim to guide clinicians and professional organisations on the use of alternate exercise prescription for older adults with cardiometabolic disease risk. With adults reporting less time to exercise, this research aims to determine if a low-moderate volume HIIT exercise program is as effective as HIIT+PRT.
Interventions
The IDEAL-EX Project will compare the effect of combined high-intensity interval training (HIIT) and progressive resistance training (PRT) against HIIT alone for improving cardiometabolic risk factors in older adults, over 12 weeks of exercise. Both groups will attend UNSW Sydney Exercise Physiology department and receive individually supervised exercise sessions, 3 non-consecutive days a week over 12 weeks by an Accredited Exercise Physiologist with at least 5 years experience. The HIIT+PRT gro
The IDEAL-EX Project will compare the effect of combined high-intensity interval training (HIIT) and progressive resistance training (PRT) against HIIT alone for improving cardiometabolic risk factors in older adults, over 12 weeks of exercise. Both groups will attend UNSW Sydney Exercise Physiology department and receive individually supervised exercise sessions, 3 non-consecutive days a week over 12 weeks by an Accredited Exercise Physiologist with at least 5 years experience. The HIIT+PRT group will perform 20 minutes of HIIT, as outlines below, including warm up and cool down, followed by 4 high-intensity PRT exercises (approximately 30 minutes as outlined below). The HIIT group will perform 20 minutes of HIIT, including warm up and cool down, and be instructed to avoid PRT during the intervention. Interventions Frequency: 3 training sessions per week, non-consecutive days (Monday, Wednesday, Friday) HIIT: Intensity: Warm-up and cool-down 50-60% peak heart rate (PHR), Interval=85-95%PHR, Rest ~70%PHR Type: Cycle ergometer Time: 20 min (Warm-up: 4 min, Intervals: 2x4min, Recovery: 2x3min, Cool-down: 2 min) Progression: Commence the 1st exercise session in Week 1 with only 1 interval at 75%PHR. From the 2nd exercise session onwards, the 2nd interval will be added and maintained. Intensity progressed by 5% resistance or Rate of Perceived Exertion (RPE) each session to ensure 85-95%PHR attained. Volume for HIIT: HIIT (frequency x intensity x time) PRT Type: Power training. Pin-loaded weight plate machines. Leg press, leg curl, seated row, chest press Intensity: 80% 1 Repetition Maximum (1RM) Volume: 3 x 8 Repetitions Pattern: Fast concentric and slow eccentric phase. Rest 1 min between sets Time: Approx 30 min Progression: Commence 50%1RM wk 1, session 1. Intensity progressed by 10% each session over 4 sessions until 80%1RM is reached. 1RM testing repeated fortnightly to assess progress and intensity adjusted accordingly. Volume for PRT: PRT (sets x reps x days) Rate of Perceived Exertion (RPE) = 8/10 will also be used to assist in adherence to 80%1RM PRT intensity protocol, as well as the HIIT training intensity. Participants adherence to the desired intervention intensity will be monitored and recorded by the supervising Accredited Exercise Physiologist as sessions attended per week, intensity achieved and session duration per session. Heart rate and blood pressure (BP) will be continuously monitored (second by second heart rate monitor, data recorded every minute with BP recorded every 3-5 minutes) during HIIT sessions. Resting measures will also be recorded before and after each exercise session.
Sponsors
Dr Belinda Parmenter
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Blinded (masking used) (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Participants will be eligible if they are 65 years or older and have two or more modifiable biological cardiometabolic disease risk factors. The following classifications/definitions of cardiometabolic disease risk factors will be used (as per the most recently updated international guidelines from the American Heart Association and International Diabetes Federation): • Body Mass Index greater than or equal to 25.0 kg/m2 • Waist Circumference greater than or equal to 94 cm (Male); greater than or equal to 80 cm (Female) (or population-specific guidelines) • Systolic Blood Pressure BP > 120mmHg and Diastolic Blood Pressure > 80 mmHg • Fasting Blood Glucose greater than or equal to 5.6 mmol/L • Total Cholesterol greater than or equal to 5.2 mmol/L • Low-density lipoprotein cholesterol greater than or equal to 2.6 mmol/L • High-density lipoprotein cholesterol greater than or equal to 1.0 mmol/L (Male); greater than or equal to 1.3mmol/L (Female) • Triglyceride greater than or equal to 1.7 mmol/L Individuals using medication for risk factor management will be identified as meeting that risk factor classification (even if levels were in normal ranges through use of pharmacotherapy).
Exclusion criteria
Exclusion criteria: • Individuals with diagnosed cardiovascular disease and/or type 2 diabetes mellitus will be excluded • Individuals will be excluded if they have current health conditions contraindicating HIIT or PRT exercise as suggested by Weston et al 2014 including: *unstable angina pectoris *uncompensated heart failure *recent myocardial infarction (<4 weeks) *recent coronary artery bypass graft or percutaneous coronary intervention (<12 months) *heart disease that limits exercise (valvular, congenital, ischaemic and hypertrophic cardiomyopathy) *complex ventricular arrhythmias or heart block *severe chronic obstructive pulmonary *cerebrovascular disease or uncontrolled peripheral vascular disease *uncontrolled diabetes mellitus *hypertensive patients with blood pressure >180/110 (or uncontrolled) or severe neuropathy; *or any other condition that is deemed contraindicated to exercise. • Participants will also excluded if they present with other unstable chronic disease including *orthopaedic or neuromuscular conditions limiting exercise ability *cognitive impairment • Participants will be excluded if they have had a medication change in the 3 months preceding the study or are non-English speaking and a suitable translator is unavailable • Furthermore individuals who have participated in structured aerobic (moderate to high intensity walking or equivalent, > 30min, 3xweek) or moderate to high intensity progressive resistance training (use of resistance training equipment including free weights and/or other forms of resistance equipment excluding theraband) in the 3 months preceding the study or are unwilling to commit to the 12 week exercise training program will be excluded.
Outcome results
None listed