Skip to content

Ultrasound guided embryo transfer for women undergoing In Vitro Fertilisation (IVF) for infertility - is it helpful for the procedure to be guided by a trained ultrasonographer and does this lead to the embryo being correctly placed more often?

Effect of sonographer guided embryo transfer versus ultrasound assisted transfer for visualisation of the bubble during embryo transfer.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12620000091909
Acronym
The GET study (Guided Embryo Transfer)
Enrollment
118
Registered
2020-02-03
Start date
2020-08-01
Completion date
2021-03-01
Last updated
2024-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Embryo transfer is the final process in the highly technical treatment of IVF. It is performed via the cervix and the embryo is placed into the uterine cavity via a fine catheter. Studies demonstrate that pregnancy rates are better when embryo transfer is performed under ultrasound guidance. Studies have also looked at the position of the bubble(fluid containing the embryo) on ultrasound following embryo transfer, with a sweet spot at 15mm from the fundal endometrium. Currently in most clinics ultrasound guidance is not performed by a person formally trained in pelvic ultrasound. The ultrasound probe is often positioned by the doctor and held by the patient whilst the doctor performs the transfer. The researchers hypothesize that performing the transfer with a trained sonographer will lead to a higher number of embryos being in the best position in the uterine cavity. We hypothesize that as compared to a patient holding the ultrasound probe, the sonographer is skilled at locating the endometrium, dynamically adjusting the probe and guiding the doctor to place the embryo in the ideal position. This study will assess the distance of the bubble from the fundal endometrium immediately following embryo transfer.

Interventions

Sonographer guided embryo transfer - the sonographer holds the abdominal ultrasound probe and guides the doctor to correctly position the embryo transfer catheter. Following embryo transfer the sonographer measures the distance of the bubble(fluid with embryo in it) from the fundal endometrium. This will potentially add on 1-2 minutes to the procedure which takes approximately 5 minutes. A picture with the bubble and measurement will be printed and the data will be entered by an independent rese

Sonographer guided embryo transfer - the sonographer holds the abdominal ultrasound probe and guides the doctor to correctly position the embryo transfer catheter. Following embryo transfer the sonographer measures the distance of the bubble(fluid with embryo in it) from the fundal endometrium. This will potentially add on 1-2 minutes to the procedure which takes approximately 5 minutes. A picture with the bubble and measurement will be printed and the data will be entered by an independent research nurse.

Sponsors

Dr Juliette Koch
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to 38 Years
Healthy volunteers
No

Inclusion criteria

All women undergoing frozen embryo transfer

Exclusion criteria

Donor egg or donor embryo

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026