Skip to content

MANTRA Self-Help Feasibility Trial

Feasibility study of an early intervention self-help psychological treatment for adult anorexia nervosa in the primary care setting.

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12620000078954
Enrollment
50
Registered
2020-01-30
Start date
2020-02-05
Completion date
Unknown
Last updated
2020-02-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Anorexia nervosa has the highest mortality rate of any mental illness, is costly for public treatment services, and has devastating effects for the affected individuals and their families. Despite this, early intervention treatment options that are evidence-based are scarce and inaccessible. This pilot project aims to assess the feasibility and early efficacy of a self-help workbook adaptation of a specialist evidence-based psychological treatment for anorexia nervosa. The intervention will be targeted to mild and subthreshold cases of anorexia nervosa. Diagnostic and neuropsychological clinical assessment will be conducted at baseline by a Clinical Psychologist. Regular within-treatment assessment of psychopathology via online questionnaires will allow efficacy indicators to be tracked over time. Qualitative feedback regarding the acceptability of the intervention will be collected from participants, together with usage metrics from their workbook. It is planned that this pilot project will lead to a larger scale line of research, including (if the pilot indicates) a larger scale randomised controlled trial.

Interventions

Evidence-based early intervention treatment options for anorexia nervosa are scarce and inaccessible. This pilot project aims to assess the feasibility and early efficacy of a self-help workbook adaptation of the Maudsley outpatient treatment for adult anorexia nervosa (MANTRA), a specialist evidence-based psychological treatment for anorexia nervosa. The workbook adaptation is a published resource developed by the treatment authors at King's College London. The workbook will be given to partici

Evidence-based early intervention treatment options for anorexia nervosa are scarce and inaccessible. This pilot project aims to assess the feasibility and early efficacy of a self-help workbook adaptation of the Maudsley outpatient treatment for adult anorexia nervosa (MANTRA), a specialist evidence-based psychological treatment for anorexia nervosa. The workbook adaptation is a published resource developed by the treatment authors at King's College London. The workbook will be given to participants by the research psychologist- being a self-help intervention, the participant will then work through the intervention themselves. The intervention will be targeted to mild and subthreshold/atypical cases of anorexia nervosa. The treatment targets disordered eating symptomology together with each element of the cognitive-interpersonal maintenance model of anorexia nervosa (emotional dysregulation, perfectionism, response of close others, biases in neurocognitive profile and poor identity formation). The workbook includes both informational readings and pen and paper based exercises. Participants will be provided with a suggested reading schedule (1 small chapter per week, or 1 large chapter per fortnight - approximately 45-60 minutes per week) and complete the workbook independently over a 12-week period. Uptake of the intervention (adherence) will be measured by participant self report at each of the questionnaire timepoints (what page they are up to). Additionally, participants will be asked to bring the workbook with them to the 12-week follow-up assessment appointment, where the researcher will take a count of the number of pen & paper based exercises completed (written space for these provided within the workbook). Materials: A Cognitive-Interpersonal Therapy Workbook for Treating Anorexia Nervosa: The Maudsley Model Hardcover (Schmidt, Startup & Treasure, 2018)

Sponsors

University of Auckland
Lead SponsorUniversity

Study design

Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Participants will be 18 years or older, medically stable, and meet criteria for mild or subthreshold anorexia nervosa, as per DSM-V (APA, 2013) criteria (Body mass index > 17.0 BMI).

Exclusion criteria

Participants with current or prior history of psychosis, current or prior specialist treatment for an eating disorder, or current suicidal ideation will not be entered into the study.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026