None listed
Conditions
Brief summary
The current proposal will assess the different taste perceptions between allergic individuals and non-allergic individuals which we hypothesize to be associated with single nuclear polymorphisms of taste receptor genes. A further study of the mechanisms underlying in taste receptors and immune cells will be carried out by evaluating the levels of taste receptor genes expressed in immune. Medically diagnosed food allergic and non-allergic cohorts will be recruited from the Allergy Medical Group, Queensland Allergy Services and the University of Queensland.
Interventions
The trial requires participants to taste sample solutions (in water) of bitter, sweet, umami, fatty acid, salty and sour tastants, and taste (not eat nor drink) some hypoallergenic foods such as milk formulas to compare taste profiles (bitter intensity, sweet intensity, etc.) and tell investigators about their preference, flavour intensity and pleasantness. Each sample will not exceed 5 ml of solution. The volunteers are asked to taste the solution in a small sip and spit it out.
The total dura
The trial requires participants to taste sample solutions (in water) of bitter, sweet, umami, fatty acid, salty and sour tastants, and taste (not eat nor drink) some hypoallergenic foods such as milk formulas to compare taste profiles (bitter intensity, sweet intensity, etc.) and tell investigators about their preference, flavour intensity and pleasantness. Each sample will not exceed 5 ml of solution. The volunteers are asked to taste the solution in a small sip and spit it out. The total duration of observation per participant will be less than 2 hours.
Sponsors
Queensland Allergy Service
Eligibility
Sex/Gender
All
Age
7 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
Non-food allergy individuals and food allergic individuals with a clinically diagnosed food allergy
Exclusion criteria
Those who are under medication (opioids, benzodiazepines, dihydropyridines, and antihistamines) and have health conditions, on-going allergic symptom(s) or smokers, pregnant or lactating females, have taste impairment. Food allergy patients who are allergic to tastants used in sensory evaluations.
Outcome results
None listed