None listed
Conditions
Brief summary
As a person ages there is a gradual decline in bone health and an increased risk of falling which, when combined, increases the risk of fractures. Weight gain is common after menopause, however weight loss leads to even greater bone loss and greater risk of fractures. This study will help to determine whether the high-load resistance training or home-based exercise are effective strategies for maintaining bone strength and physical function during weight loss.
Interventions
The study is a two-arm, randomised controlled exercise intervention trial. Eligible volunteers will be randomly allocated to one of the two eight-month, twice-weekly, 30-minute exercise programs; either a supervised high-intensity progressive resistance training and impact loading group, or an unsupervised home-based low intensity resistance training and flexibility training group.
Arm 1 - Supervised high-intensity progressive resistance and impact training (HiRIT).
Sessions will be supervis
The study is a two-arm, randomised controlled exercise intervention trial. Eligible volunteers will be randomly allocated to one of the two eight-month, twice-weekly, 30-minute exercise programs; either a supervised high-intensity progressive resistance training and impact loading group, or an unsupervised home-based low intensity resistance training and flexibility training group. Arm 1 - Supervised high-intensity progressive resistance and impact training (HiRIT). Sessions will be supervised by a qualified trainer in a group setting with a maximum trainer to participant ratio of 1:6. Three compound movement exercises using Olympic weights (deadlifts, squats, and presses), along with a weight-bearing impact loading exercise (drop jumps) as per the LIFTMOR protocol (Watson et al., Journal of Bone and Mineral Research, 2017). Five sets of five repetitions will be performed for each exercise and intensity will be progressed to maintain 80-85% 1 repetition maximum and when deemed safe and appropriate by the trainer. Participants will be afforded up to 3 minutes rest between sets. Training diaries will be used to record participant attendance to training session and to track the weights lifted over the duration of the intervention. Compliance to the training programs will be determined by the number of sessions attended as a percentage of the total number of possible sessions.
Sponsors
Griffith University
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Investigator)
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Overweight (body fat > 35% or BMI > 30) post-menopausal women (>60 years) with low bone mass (>1SD below age-matched mean BMD) who are otherwise in good general health, community ambulant without a walking aid, and currently attempting to lose weight via non-exercise means (e.g. diet) that are willing to undertake an 8-month exercise program twice per week.
Exclusion criteria
Recent and regular participation in high intensity resistance or impact training Less than five years post menopause Recent fracture or musculoskeletal condition/s (e.g. low back pain or osteoarthritis) or joint surgery preventing physical activity Contraindications for participating in heavy physical activity (i.e. uncontrolled cardiovascular disease) Metallic implants (e.g. staples, joint replacement) or foreign bodies (e.g. shrapnel) More than two x-ray examinations in the past year or radiation treatment Cancer Cognitive impairment Certain types of current physical activity Medications and/or conditions know to influence bone health (e.g. Paget’s Disease)
Outcome results
None listed