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Imagery Rescripting of Intrusive Autobiographical Memories in Depression - A Case Series

Imagery Rescripting of Intrusive Autobiographical Memories in Depression - A Case Series

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12619001713189
Enrollment
5
Registered
2019-12-05
Start date
2019-09-12
Completion date
2020-06-30
Last updated
2019-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The present study is a case series where individuals with a diagnosis of major depressive disorder will be offered 12 sessions of imagery rescripting. The first aim will be investigated using cross-sectional data collected at the baseline phase: to examine the prevalence, content, characteristics and responses to intrusive memories reported by participants. The second aim is to determine whether participants endorse features of maladaptive schema modes - as outlined in Young's (2006) Schema Mode Model. The final aim is to evaluate whether a 12-session imagery rescripting intervention is efficacious at reducing symptoms of major depressive disorder, as well as intrusive memories and rumination. Hypotheses: 1. Participants will report frequent and distressing intrusive memories about a range of negative autobiographical events. Intrusive memories will be associated with the severity and maintenance of depressive symptomology. 2. Intrusive memories that are experienced as predominantly sensory will be associated will greater distress than those experiences as predominantly verbal. 3. Rumination will be positively associated with intrusive memories. 4. Participants will report activation of maladaptive child, parent and coping schema modes. Schema mode activation will be associated with the severity and maintenance of depressive symptomology. 5. Following 12 sessions of imagery rescripting, participants will experience less frequent and distressing intrusive memories, as well as reduced rumination and depression symptomology.

Interventions

Participants will attend 12 90 minute sessions, conducted weekly, in which they will be guided by the psychologist to identify an autobiographical event linked to their intrusive memories. The participant will be asked to rate the belief and affect associated with the memory out of 100. Participants will then be guided to imaginally relive the event in as much detail as possible, describing what is occurring and how they feel. During the reliving, participants will be asked what they need to c

Participants will attend 12 90 minute sessions, conducted weekly, in which they will be guided by the psychologist to identify an autobiographical event linked to their intrusive memories. The participant will be asked to rate the belief and affect associated with the memory out of 100. Participants will then be guided to imaginally relive the event in as much detail as possible, describing what is occurring and how they feel. During the reliving, participants will be asked what they need to change in the scene in order to feel better emotionally. The therapist and participant will then collaboratively rescript the memory accordingly. Participants will then be asked to re-rate their original belief and affect about the event. In subsequent sessions further modifications to the memory will be conducted as required, and additional intrusive memories will be identified and rescripted.

Sponsors

University of Technology Sydney
Lead SponsorUniversity

Study design

Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Inclusion criteria: adult (minimum 18 years old); fluency in English; ability to provide informed consent; meets Diagnostic and Statistics Manual (DSM-5) criteria for a diagnosis of Major Depressive Disorder and experiences frequent and distressing intrusive memories of at least one autobiographical event.

Exclusion criteria

Exclusion criteria: current suicidal or homicidal ideation or significant risk of harm to self or others; current psychotic symptoms or a psychotic disorder (bipolar disorder, schizophrenia or related psychosis), substance use disorder, current engagement in psychological treatment, commencement or change in anti-depressant medication 8 weeks prior to commencement of trial.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026