None listed
Conditions
Brief summary
Near-infrared spectroscopy (NIRS) measures regional oxygen saturation (rSO2) of the underlying tissue. During air transport the effects of altitude on patient oxygenation are of special importance. With increasing altitude, barometric pressure decreases and as a result also the partial pressure of oxygen. The result is lower oxygen saturations. The primary aim of the current study is to investigate how cerebral and splanchnic oxygen saturation in critically ill children transported in air ambulance was affected by flight with cabin pressurization corresponding to 5000 feet or higher.
Interventions
A cerebral and a splanchnic Near-infrared (NIRS) sensor were used to register regional oxygen saturation (rSO2) during transport of critically ill children in air ambulance. Participants were monitored for the entire flight with flights ranging from 60 minutes to 6 hours. The electronically stored data from the INVOS 5100C from 39 patients were afterwards extracted and examined to investigate how cerebral and splanchnic oxygen saturation was affected by flight with cabin pressurization corresponding to altitudes at 5000 feet or higher.
Sponsors
Eligibility
Inclusion criteria
Children scheduled for inter-hospital transport by a specialized pediatric transport team at the Pediatric Intensive Care Unit (PICU) at the Astrid Lindgren Children’s Hospital, Karolinska University Hospital in Stockholm, Sweden.
Exclusion criteria
Flights with an estimated duration less than 50 minutes and flights with a need for sea level cabin altitude. Lack of informed consent, participation in any other clinical research study,