None listed
Conditions
Brief summary
Stroke reperfusion therapy is time critical. Improving pre-hospital diagnostic accuracy including likelihood of large vessel occlusion (LVO) can aid in making efficient and appropriate diversion decisions and has the potential to improve onset-to-treatment time. This study aims to investigate whether pre-hospital telestroke improves diagnostic accuracy and accurate identification of potential reperfusion candidates compared with other currently used paramedic scoring systems. This is a pragmatic community based cluster randomised controlled trial in the greater Wellington area comparing specialist telestroke assessments inside the ambulance with routine use of the FAST (‘Face, Arm, Speech, and Time’) plus the PASTA score to correctly identify stroke reperfusion candidates including LVO patients. The PASTA score is a New Zealand adaptation of the Los Angeles Motor Scale (LAMS) where LAMS >2, Glasgow Coma Scale >5, age >15, and absence of glucose derangement and seizure are used as positive predictors of likely LVO. The target sample size is 55 patients in each study arm to identify 20% difference in diagnostic accuracy using telestroke over PASTA with 90% power and 5% error. This study includes an economic analysis of resource use in relation to patient benefit.
Interventions
The interventions consists of remote neurologist support for paramedics inside an ambulance to help diagnose whether a patient has truly suspected a stroke and whether they are eligible for reperfusion therapy. The support is rendered using iPads installed inside the ambulance connecting to the remote neurologist via videconferencing software. The workflow is outlined for the paramedics inside the ambulance using laminated cards. The videoconferencing approach allows the neurologist to make a verbal and visual assessment of the patient. This trial only assesses the diagnostic accurate of this approach, does not effect patient management, and does not involve any medications. Each individual patient will be assessed inside the ambulance only once during the ambulance transfer and each assessment will take between 5 and 15 minutes. The 'intervention' is an assessment itself that is standardised although we expect some degree of inter-assessor variation which is not dissimilar to any acute stroke assessment in light of the fact that patients vary between one another requiring some adaptation of the assessment approach. The control arm will be using standard pre-hospital paramedic assessment scores (FAST and PASTA) to confirm stroke diagnosis and likelihood of being a reperfusion therapy candidate. The scores consist of a few items around the patient's presentation (eg face weakness, speech difficulties, arm weakness) that are added up to determine diagnosis.
Sponsors
Study design
Eligibility
Inclusion criteria
Patient identified by paramedic as possible stroke (triggering a pre-hospital stroke alert) and transported within one of the trial ambulances to Wellington Hospital.
Exclusion criteria
Patient presents outside of trial operating hours (8am to 10pm M-S)