Abnormal heart rate rise in a population of Afro-Caribbean patients with cardiac amyloid disease

a) Lung function test and cardiopulmonary exercise testing will be performed on the same day. Typically, lung function tests will be performed before exercise testing b) Testing will be performed once at patients inclusion. Duration of lung function evaluation is 45 min and duration of cardiopulmonary exercise testing is 60 min. c) Doctors (cardiologists) will be involved in lung function test and cardiopulmonary exercise testing as well. d) Lung function test includes spirometry and lung plethysmography. Cardiopulmonary exercise testing includes measures of ventilation and respiratory gas parameters during cycling exercise. Measuring systems relies on breath-by-breath analysis techniques. Oxygen and carbon dioxide gas analyzers are usually incorporated in a “metabolic cart” designed specifically for functional testing. Respiratory volumes are computed by integrating the air flow signals over the time of inspiration and expiration. Average minute volumes are derived from the breath-by-breath data multiplied by the respiratory rate