None listed
Conditions
Brief summary
Cellulite is as an "orange peel" appearance on the skin surface that is associated with poor microcirculation, weight change, race and heredity, but there is little consensus about its cause. The objective of this study is to determine the effect of a caffeine cream that we have developed on cellulite appearance, thigh circumference and skin fold thickness. We will also assess participants' perception of the sensorial qualities of the caffeine cream. Participants will apply the cream to one thigh and a placebo cream to the other thigh twice daily for 12 weeks. Assessments will be done at week 4, 8 and 12. We anticipate that the developed cream will target caffeine to the skin tissue and reduce cellulite.
Interventions
a) The cream is to be applied twice a day (morning and night).
b) On each application: rub approx 2g cream on each thigh for 30 sec - the amount will be demonstrated on a spatula
c) Repeat the application each day for a total duration of 12 weeks. A diary is provided for recording each application.
d) At completion of the study (12 weeks) the diary and cream jars will be collected
Sponsors
Curtin University
Study design
Allocation
Randomised controlled trial
Intervention model
Other
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Healthy volunteers
No
Inclusion criteria
We are recruiting only female participants with cellulite present on thighs
Exclusion criteria
cellulite treatment in previous 3 months, scarring or surgery at treatment site in previous 12 months
Outcome results
None listed