None listed
Conditions
Brief summary
Diet remains a cornerstone of type 1 diabetes (T1D) management, with carbohydrate intake having the greatest impact on insulin requirements and blood glucose fluctuations. However, there is limited scientific evidence comparing the effect(s) of different levels of carbohydrate intake on T1D management. A T1D outpatient centre in Perth WA has been actively implementing carbohydrate-focused diet interventions, including low-carbohydrate diets, for T1D. This presents an opportunity to conduct a chart review to better understand the effect(s) of varying levels of carbohydrate on T1D management outcomes, and to identify and describe effective dietary approaches for this clinical population. We expect that low-carbohydrate diets (<130 g/day) will lead to improvements in T1D management due to reduced error rates in calculating exogenous insulin requirements.
Interventions
a) Carbohydrate-focused dietary interventions, including any intervention that prioritises the amount and/or type of dietary carbohydrate to be consumed amount, that are designed and delivered by a Credentialed Diabetes Educator and Accredited Practising Dietitian. It is expected that carbohydrate-focused dietary interventions will include low- (<26% total energy as carbohydrate), moderate- (26-45% total energy as carbohydrate) and high-carbohydrate (45-65% total energy as carbohydrate) diets.
b
a) Carbohydrate-focused dietary interventions, including any intervention that prioritises the amount and/or type of dietary carbohydrate to be consumed amount, that are designed and delivered by a Credentialed Diabetes Educator and Accredited Practising Dietitian. It is expected that carbohydrate-focused dietary interventions will include low- (<26% total energy as carbohydrate), moderate- (26-45% total energy as carbohydrate) and high-carbohydrate (45-65% total energy as carbohydrate) diets. b) Participant involvement is minimal, with a total of 20 minutes expected. Participants are required to provide informed consent to access medical records and will be asked to complete a short online questionnaire for collection of demographic characteristics and general health information. This includes age, sex, ethnicity, religion, education level, duration of diabetes, co-morbidities (i.e., other active diseases/conditions), and medication use. Participants may also be contacted via telephone for clarification of any information they provide. c) The duration of observation per participant may be from 2 weeks up to 2 years. The minimum duration of exposure to the diet intervention for inclusion is 2 weeks, and we expect that participants will have been exposed to the diet for varying durations.
Sponsors
Jessica Turton
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
To be included in the study, participants must be adults (18-60 years) with previously diagnosed type 1 diabetes (T1D), attended at least two consultations (greater than or equal to 2 weeks apart) with the research site’s (Type 1 Diabetes Family Centre in Perth, Western Australia) Credentialed Diabetes Educator & Accredited Practising Dietitian (CDE/APD) for dietary advice regarding a reduced-carbohydrate diet, and have the following data items available: sex, age, prescribed carbohydrate amount (as grams per day, %TEI or a clear description of the types of foods to include and avoid) and pre-post values for at least one primary or secondary clinical outcome. The primary outcome is HbA1c and estimated A1c (eA1c), and secondary outcomes are glycaemic variability, mean fasting blood glucose levels, total daily insulin use, and patient-reported well-being.
Exclusion criteria
There are no key exclusion criteria. Eligible participants must satisfy the key inclusion criteria only.
Outcome results
None listed