None listed
Conditions
Brief summary
Managing weight gain during pregnancy is important for positive health outcomes of both mother and infant. Currently, best practice guidelines for pregnancy follow a weight focused model with recommendations of weight gain during pregnancy based on pre-pregnancy body mass index (BMI). However, unfavourable changes in body composition (e.g. excessive body fat) result in poor health outcomes rather than weight gain in isolation. Research is lacking into body composition changes during pregnancy and its link to infant weight and body composition at birth and in early life. The Koru Study will measure body composition changes during pregnancy using air displacement plethysmography (BodPod®) and also infant body composition in early life using a Peapod®. Energy expenditure will be investigated by measuring physical activity during and post pregnancy in combination with dietary intake and resting metabolic energy. Dietary advice received during pregnancy will also be investigated.
Interventions
As an observational study, the objectives are to investigate body composition changes as measured by air displacement plethysmography (BODPOD®) during each trimester of pregnancy and postnatally up to 4 months (6 visits in total); Infant body composition changes as measured by air displacement plethysmography (PEAPOD®) at three visits until the infant is 4 months of age. To investigate dietary advice received during each trimester of pregnancy and postnatally at 4 months as measured by questio
As an observational study, the objectives are to investigate body composition changes as measured by air displacement plethysmography (BODPOD®) during each trimester of pregnancy and postnatally up to 4 months (6 visits in total); Infant body composition changes as measured by air displacement plethysmography (PEAPOD®) at three visits until the infant is 4 months of age. To investigate dietary advice received during each trimester of pregnancy and postnatally at 4 months as measured by questionnaire. To investigate energy intake and physical activity measured via 4-day diet record and physical activity monitor (namely accelerometer) respectively, during each trimester of pregnancy and postnatally at 4 months. Investigating micronutrient status (namely iron, iodine, selenium and folate) as measured by blood and urine sampling during each trimester of pregnancy and postnatally up to 4 months. To investigate changes in resting metabolic rate during each trimester of pregnancy and postnatally up to 4 months.
Sponsors
Dr Louise Brough
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
The target population for the study is healthy pregnant women who have conceived naturally with a singleton pregnancy only. Since the study will follow participating pregnant women and their infants until the baby is 4 months old, continued participation requires that the infant does not contract or suffer from any serious on-going health problems. Postpartum women's newborn infants will be included in the study if they are healthy. These infants can be a boy or girl, and are aged between 7-14 days old and 4 months.
Exclusion criteria
Previous pregnancy history of preterm birth, gestational diabetes, preeclampsia, and hypertension. Multiple pregnancy Pregnancy which has resulted in a serious on-going health condition(s)
Outcome results
None listed