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Evaluating the health beneficial properties of coloured rice consumption in healthy populations

The bioavailability, antioxidant and anti-inflammatory properties of coloured rice consumption in healthy populations

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12619001442190
Enrollment
22
Registered
2019-10-17
Start date
2019-01-07
Completion date
2019-02-28
Last updated
2019-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The aim of this study is to evaluate the antioxidant and anti-inflammatory properties in healthy populations post-coloured rice consumption. Participants will have blood samples taken before & at set time points after rice consumption. The blood samples will be analysed for antioxidant and inflammation-related biomarkers. A one week washout period will be implemented for each participant for each variety tested. The intent of this study is to identify if coloured rice consumption has the ability to alleviate risk factors associated with the development of lifestyle diseases such as cardiovascular disease.

Interventions

1. Participants in a fasting state (minimum 8 hours, no food, water only) will be prepared for cannulation. The participants are either called or text messaged to remind them of their study fasting requirements. An intravenous cannula will be inserted into the arm vein using standard cannulation procedures (Guideline for PIVC Insertion and Post Insertion Care in Adult Patients, NSW Health) by a trained phlebotomist. 2. Baseline blood samples (25 mL) will be obtained and the participants will con

1. Participants in a fasting state (minimum 8 hours, no food, water only) will be prepared for cannulation. The participants are either called or text messaged to remind them of their study fasting requirements. An intravenous cannula will be inserted into the arm vein using standard cannulation procedures (Guideline for PIVC Insertion and Post Insertion Care in Adult Patients, NSW Health) by a trained phlebotomist. 2. Baseline blood samples (25 mL) will be obtained and the participants will consume a serving of plain cooked coloured rice (one cup or 200 g) and have 20-minutes to consume the rice serving. 3. After rice consumption, blood samples (25 mL at each time point) will be taken at regular time intervals 0.5, 1, 2 ,4 ,6 hours post rice consumption. 4. The cannula will be removed and the site covered with sterile gauze. 5. A one week of wash out between cross over 2 (week 2 - day 7) and 3 (week 3 - day 14) will be applied. The order of rice varieties (black, red and brown rice) served to the participants is randomised for each participant over the 3 weeks (e.g. Participant 1 - Purple, brown, red; Participant 2 - red, purple brown). This randomisation is completed using Microsoft Office Excel.

Sponsors

Dr. Abishek Santhakumar
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

• Healthy (BMI 18.5 - 24.9 ) • Non-smoker • Caucasian • Male or Female (18 - 65 years) • No current or medical history of Chronic diseases • Non-pregnant • Not currently taking anti-inflammatory, anti-dyslipidaemic or anti-clotting medications • No known problems with venepuncture • Not currently taking multivitamin supplements

Exclusion criteria

None

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026