None listed
Conditions
Brief summary
Evidence from scientific studies demonstrate positive effects of ingredients Ginseng (Cereboost), Bacopa and Coffee fruit extract as isolated components, on various mechanisms that impact cognitive performance and mood. For example, Ginseng and Gingko have been shown to enhance cognitive performance after acute dosing whilst Bacopa has been shown to have effects primarily with chronic dosing. To date however, the combination of three ingredients at established dosages of effect have not been evaluated. This research seeks to conduct same day testing to understand any changes in cognitive performance and brain activation patterns using standardized cognitive tasks and a non-invasive functional near infrared spectroscopy (fNIRS), measured both before and after taking the active or placebo supplement.
Interventions
An acute (same day), double-blinded, placebo-controlled between conditions (active and placebo supplementation) intervention, where participants consume a single, 2 tablet dose (500mg) in a 2 hr period of either the active (herbal combination of Bacopa 300mg, Ginseng 100mg, and Coffee fruit extract 100mg) or placebo (microcrystalline cellulose 581mg).
Participants complete a series of thinking and memory tasks pre and post consumption.
Tolerance to tablet consumption was monitored through dire
An acute (same day), double-blinded, placebo-controlled between conditions (active and placebo supplementation) intervention, where participants consume a single, 2 tablet dose (500mg) in a 2 hr period of either the active (herbal combination of Bacopa 300mg, Ginseng 100mg, and Coffee fruit extract 100mg) or placebo (microcrystalline cellulose 581mg). Participants complete a series of thinking and memory tasks pre and post consumption. Tolerance to tablet consumption was monitored through direct observation by study personnel and through a specific tolerance question, " how are you feeling now?".
Sponsors
Central Queensland University
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Blinded (masking used) (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
Healthy adults aged 18- 60 years, without major medical conditions, such as diabetes, cardiovascular disease, acute or terminal illness; BMI below 35, moderate alcohol consumption, no medication changes for the management of health conditions within last 6 weeks, no current or recent history of taking medications for mood disorders and/or previous history of neurological conditions as these conditions have been shown to be related to impaired cognitive performance.
Exclusion criteria
Pre-existing medical conditions, including diabetes, cardiovascular disease, medication changes for the management of health conditions within last 6 weeks, current or recent history of taking medications for mood disorders and/or previous history of neurological conditions.
Outcome results
None listed