None listed
Conditions
Brief summary
The aim of this project is to determine if there is a difference in microbial community between responsive and non-responsive sites. A secondary aim is to determine if there is a difference in microbial community between responded and healthy sites. The objective is to establish the microbial community profile associated with sites that respond poorly to periodontal treatment. The specific hypothesis tested is whether certain subgingival microbial profiles are associated with poor response to periodontal treatment in a prospective longitudinal clinical study in a Melbourne population. Achieving the above aim may assist with a better understanding of the polymicrobial aetiology of chronic periodontitis and its effect on treatment. The establishment of a microbial community profile associated with sites that respond poorly to periodontal treatment may allow for the pre-operative identification and allow more targeted treatment of these sites.
Interventions
Non-surgical periodontal treatment including subgingival debridement (removal of subgingival plaque and calculus). This treatment is the currently recognised best practice treatment for periodontitis. This treatment involves scraping the teeth with hand scalers, the use of an ultrasonic scaler to remove calculus, polishing the teeth with a professional polishing paste, and oral hygiene instructions.
The treatment will be performed by a registered dentist in a specialist-in-training program. The
Non-surgical periodontal treatment including subgingival debridement (removal of subgingival plaque and calculus). This treatment is the currently recognised best practice treatment for periodontitis. This treatment involves scraping the teeth with hand scalers, the use of an ultrasonic scaler to remove calculus, polishing the teeth with a professional polishing paste, and oral hygiene instructions. The treatment will be performed by a registered dentist in a specialist-in-training program. The treatment will be carried out over 4 x 2 hr appointments over a 4-6 week period. The treatment will be carried out in the Periodontics department of the Royal Melbourne Dental Hospital. All interventions will be recorded in the patient file by the practicing clinician and checked off the patient's treatment plan.
Sponsors
Samantha Byrne
Study design
Allocation
Non-randomised trial
Primary purpose
Treatment
Eligibility
Sex/Gender
All
Age
35 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
Patients with periodontitis as determined by the presence of at least 4 diseases single-rooted teeth defined by >/= 1 site a the tooth with a probing pocket depth of >/= 5 mm with bleeding on probing.
Exclusion criteria
Use of antibiotics in the prior 3 months, pregnancy or lactation, systemic conditions which may affect the progression of periodontitis (eg diabetes), any condition requiring premedication prior to treatment, long-term therapy with non-steroidal anti-inflammatory drugs and history of periodontal treatment within the past 3 months.
Outcome results
None listed