Cerebral oxygenation during neonatal intubation

Cerebral oxygenation during neonatal intubation: an observational study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12619001276145

Enrollment

Registered

2019-09-16

Start date

2020-09-13

Completion date

2021-04-18

Last updated

2022-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This is a sub-study of the SHINE randomised controlled trial (ACTRN12618001498280). In this sub-study, we will also monitor oxygen supply to the brain (by placing a sensor on the forehead). We hope that this will give further information about the changes in oxygen delivery to the brain during placement of breathing tube for babies.

Interventions

Observational study of cerebral oxygenation using Near Infra Red Spectroscopy (NIRS) during neonatal intubation. This is a sub-study of the SHINE trial (ANZCTR 12618001498280) which is examining the use of nasal high flow therapy during neonatal intubation. This is an additional observational study at the Royal Women's Hospital, Melbourne, Australia, only. This sub-study will compare NIRS in those neonates receiving nasal high flow during intubation and those not receiving nasal high flow during

Eligibility

Sex/Gender

All

Age

0 to 6 Months

Healthy volunteers

Inclusion criteria

1. Any neonate undergoing endotracheal intubation in the delivery room or NICU AND 2. HR >120bpm at the time of randomisation 3. Prospective consent obtained from parent/guardian 4. Participation in the study ACTRN12618001498280

Exclusion criteria

1. Requirement for immediate endotracheal intubation as determined by the treating clinician, without time for randomisation and potential application of nHF, eg. active cardiopulmonary resuscitation 2. Heart rate <120 bpm at the time of randomisation 3. Contraindication to nHF use (eg. congenital nasal anomaly, congenital diaphragmatic hernia, abdominal wall defects) 4. Nasal intubation planned

Outcome results