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A retrospective study on the utility of neck MRI scans following normal CT and Xray

A retrospective analysis of the utility of cervical spine MRI in patients with normal CT and plain radiographs

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12619001261101
Enrollment
301
Registered
2019-09-12
Start date
2017-07-28
Completion date
2017-12-02
Last updated
2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Following acute blunt cervical injury, there is ongoing debate regarding the reliability of Computed Tomography (CT) and plain radiographs versus the need for Magnetic Resonance Imaging (MRI). The objectives of this study was to determine the incidence of new findings found on MRI following normal CT or plain radiographs in patients with persistent cervical tenderness, focal neurology or in patients who are clinically unevaluable; and to assess if the management was altered following MRI results.

Interventions

Following acute blunt cervical trauma, spinal cord injury carries a heavy disease burden. With such high morbidity at stake, it is crucial not to miss the diagnosis of cervical spine injuries in order to prevent spinal cord injuries. Establishment of cervical spine clearance is a common clinical conundrum encountered by health care professionals. CT has superseded plain radiographs as the primary screening modality. Nonetheless, a proportion of cervical injuries are caused by soft tissue injurie

Following acute blunt cervical trauma, spinal cord injury carries a heavy disease burden. With such high morbidity at stake, it is crucial not to miss the diagnosis of cervical spine injuries in order to prevent spinal cord injuries. Establishment of cervical spine clearance is a common clinical conundrum encountered by health care professionals. CT has superseded plain radiographs as the primary screening modality. Nonetheless, a proportion of cervical injuries are caused by soft tissue injuries which may not be detected on CT scan alone. In patients with normal CT scans and plain radiographs who have persistent neck pain, focal neurology or are clinically unassessable due to altered mental status, there is ongoing debate regarding the reliability of CT scans in excluding cervical injuries versus the need for further imaging with MRI. Albeit frequently performed, the utility and cost-effectiveness of MRI remains an ongoing debate and requires further validation. Thus, the primary objective of this study was to determine the incidence of additional findings on MRI imaging that were not previously detected on CT scan. A single-centre, retrospective analysis was conducted at Tertiary care, Level 1 Trauma Centre in Western Australia using keyword searches on the PACS-RIS (Picture Archiving and Communication System- Radiology Information System) imaging database including the following terms: “cervical”, “injury”, “rupture”, “sprain”, “strain”, “tear”, “tenderness”. The search included scans performed from 1st January 2004 to 2nd October 2017. No participant involvement was required in this study. Patients who had a normal CT scan or plain radiographs and subsequently underwent an MRI scan to rule out potential cervical injuries were included in the study. Reports of the MRI scans were obtained and the incidence of abnormalities found on MRI was evaluated as the primary endpoint. The MRI must be performed within the same admission as the acute injury. The secondary endpoint was the percentage of patients with normal CT scans or plain radiographs whose management was altered following additional abnormalities found on MRI. To quantify this, management of patients was followed up from discharge summaries, inpatient notes and/or outpatient clinic notes from the medical records.

Sponsors

Dr Jean Ai Adeline Yap
Lead SponsorIndividual

Eligibility

Sex/Gender
All
Age
16 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Patients with potential cervical injuries following an acute injury due to blunt trauma with normal CT scans or plain radiographs. Patients who underwent subsequent MRI scans after normal CT scan or plain radiographs, either internally at Royal Perth Hospital or externally from other sites with images available on PACS-RIS and full report accessible. Patients with persistent cervical tenderness, abnormal neurology or remain clinically unevaluable due to various aetiologies such as traumatic brain injury, drug intoxication, sedation, intubation or pre-existing neurological conditions

Exclusion criteria

Patients with any abnormality on CT scan or plain radiography were excluded from this study.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026