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Early home-based pulmonary rehabilitation after hospitalisation in chronic obstructive pulmonary disease (COPD)

The effect of early home-based pulmonary rehabilitation after hospitalisation on hospital readmission in chronic obstructive pulmonary disease (COPD)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12619001122145
Enrollment
157
Registered
2019-08-12
Start date
2020-01-13
Completion date
2024-06-26
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

After a period of hospitalisation, pulmonary rehabilitation can improve symptoms and function and reduce healthcare costs in people with chronic obstructive pulmonary disease (COPD). Yet less than 10% of people with COPD access pulmonary rehabilitation after a hospital stay. This multi-site randomised controlled trial will examine the benefits and costs of home-based pulmonary rehabilitation undertaken immediately following hospitalisation, compared to usual care, for people with COPD. It is hypothesised that Early HomeBase pulmonary rehabilitation will reduce hospital readmissions, and provide clinically significant improvements in exercise capacity and health-related quality of life, which are greater than those seen in the usual care group.

Interventions

People who agree to take part in the study will be randomly allocated to undertake pulmonary rehabilitation at home (early HomeBase)(commenced within 2 weeks of hospital discharge) or usual post-hospital care. People allocated to undertake early home-based pulmonary rehabilitation (n=83) will receive, in addition to standard (usual) care, an initial home visit from a physiotherapist to establish the exercise training program, facilitate setting of exercise goals and to ensure safety. This will b

People who agree to take part in the study will be randomly allocated to undertake pulmonary rehabilitation at home (early HomeBase)(commenced within 2 weeks of hospital discharge) or usual post-hospital care. People allocated to undertake early home-based pulmonary rehabilitation (n=83) will receive, in addition to standard (usual) care, an initial home visit from a physiotherapist to establish the exercise training program, facilitate setting of exercise goals and to ensure safety. This will be followed by seven once-weekly phone consultations with a physiotherapist, specially trained in motivational interviewing, to undertake self-management training and promote exercise progression. The total program duration is 8-weeks. The home-based exercise training program will consist of a walking program (including use of a pedometer) and light weights for the arms and legs using readily available equipment in the home (eg. water bottles). Participants will be encouraged to undertake exercise on at least 5 days in the week, and to record their exercise participation in a home exercise diary. The overall goal of the program is for participants to work towards achieving at least thirty minutes of aerobic training on most days of the week. Exercise training intensity and session duration will be individualised and guided by participants perceived breathlessness (e.g BORG breathlessness scale, range 3-4). Home exercise diaries will be reviewed during the weekly telephone call consultation with the physiotherapist. All participants will receive standard (usual) care, including medical management for their exacerbation based on COPD-X guidelines (which may include inhaled bronchodilators, systemic glucocorticoids and antibiotic therapy as indicated, controlled oxygen therapy and ventilatory assistance as required) and physiotherapy, commencing on the first day of admission. In line with guideline recommendations for management of an acute exacerbation of COPD, standard (usual) care may include referral to traditional outpatient (centre-based) pulmonary rehabilitation after discharge from hospital. Participants randomised to the intervention (early HomeBase) group will be precluded from attending outpatient pulmonary rehabiliation during the intervention period (ie. Weeks 0-10 post hospital discharge). This is to prevent participants undertaking two pulmonary rehabilitation programs at the same time (home and centre-based). Participants in the intervention group will not be precluded from referral to or attending outpatient pulmonary rehabilitation at any time during the 12 month followup period. At the beginning and end of the 8 weeks of the intervention phase, and after 12-months followup, participants will undergo measurements of functional capacity and health status. Hospital medical records and GP records will be reviewed to determine the need and frequency of hospital admissions. This will be tracked for 12 months for all participants.

Sponsors

Monash University
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
40 Years to No maximum
Healthy volunteers
No

Inclusion criteria

- Have a diagnosis of COPD - Be admitted to hospital for an acute exacerbation of their COPD - Aged 40 years and older - Able to read and speak English

Exclusion criteria

- Life expectancy less than 6 months - Comorbidities which preclude exercise training - Inability to follow verbal instructions, suffer from cognitive impairment, or have language difficulties - Unable to provide informed consent

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 14, 2026