None listed
Conditions
Brief summary
This study is designed to measure the risk factors that are important in the development of muscle relaxant anaphylaxis. It does this by comparing risk factors between two similar groups of patients that have had anaphylaxis, the only difference being that one group suffered anaphylaxis to a muscle relaxant, the other to cephazolin.
Interventions
Study involves interrogation of the Western Australian Anaesthetic Allergy Clinic Database (patient questionnaire, medical records and outcome of skin testing and blood tests). Exposure is the patient characteristics that may predispose to anaphylaxis (body mass index, gender, age, pholcodine exposure, ASA grade). Duration of observation is 6 months previous to anaphylactic reaction
Sponsors
Sir Charles Gairdner Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Inclusion criteria are intraoperative anaphylaxis in patients all of whom were exposed to a muscle relaxant during the intraoperative episode, prior to the reaction. Recruited patients either had anaphylaxis to a muscle relaxant or cephazolin
Exclusion criteria
Must be over 18, and must be able to be contacted to confirm Pholcodine exposure if not documented previously. BMI must have been documented at time of reaction or review in clinic as long as that was within 3 months of the reaction. Skin testing must have occurred within 5 years of intraoperative reaction.
Outcome results
None listed