None listed
Conditions
Brief summary
This project seeks to determine the feasibility and effectiveness of timing exercise to control blood glucose levels and reduce cardiovascular risk in people with Type 2 Diabetes. People with Type 2 Diabetes will be randomised to standard care alone or with time of exercise specified to coincide with/avoid blood glucose peak. It is hypothesised that individually prescribing ‘the time’ a person should exercise will optimised blood glucose control and attenuate peak blood glucose when compared to standard care and exercise at times other than peak.
Interventions
People with Type 2 Diabetes will be advised to engage in moderate intensity walking (Borg RPE 11-13) physical activity every day for 5 months (~150 min/week, ~22 min/day). Participants will be randomised to 1 of 3 groups; 1) 8-wk Waitlist Control (standard care 150 min/wk, exercise at any time) followed by randomised interventions; or 2) daily Exercise at peak hyperglycaemia (identified individually from CGM data); 3) daily Exercise not at peak (identified individually from CGM data. The interve
People with Type 2 Diabetes will be advised to engage in moderate intensity walking (Borg RPE 11-13) physical activity every day for 5 months (~150 min/week, ~22 min/day). Participants will be randomised to 1 of 3 groups; 1) 8-wk Waitlist Control (standard care 150 min/wk, exercise at any time) followed by randomised interventions; or 2) daily Exercise at peak hyperglycaemia (identified individually from CGM data); 3) daily Exercise not at peak (identified individually from CGM data. The intervention period is 8 weeks, 5 sessions are supervised by an Accredited Exercise Physiologist and the majority of sessions performed at home unsupervised. Adherence will be assessed using accelerometry mid 8-wk intervention, post 8-wk intervention and after a 3 month free living period where participants will be asked to continue their prescribed exercise intervention independently and without contact.
Sponsors
University of Wollongong
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
• Type 2 Diabetes *BMI between 27-40kg/m2 • HbA1c between 6.5-9% • Non-smoker (for >6 months prior to study start) • Stable weight for previous 3 months (± 4kgs) • Stable medications for previous 3 months
Exclusion criteria
• Presence of any absolute contraindications to exercise (including musculoskeletal and joint) • Known CVD or prior history of CVD • Uncontrolled Hypertension • Prior history of kidney and/or liver disease • Diagnosed Neuropathy • >150 minutes exercise/week
Outcome results
None listed