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The effect of local anesthetic infiltration to the nerves which lies in the axilla on postoperative analgesia and opioid consumption in cancer breast surgery.

Comparison of PECs II block with Axillary infiltration of local anesthetic on postoperative analgesia in patients undergoing cancer breast surgery : a randomized clinical trial.

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12619001029189
Enrollment
40
Registered
2019-07-18
Start date
2019-08-15
Completion date
2019-10-15
Last updated
2019-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

In our study we introduced a new technique for postoperative control of pain in patients undergoing breast surgery. The technique consisted of infiltrating the axillary fat area with ropivacaine by using ultrasound. Hypothesis: the new technique is effective as Pec's II block on postoperative analgesia.

Interventions

Thirty minutes prior induction of general anesthesia, Axillary Infiltration group: Patient in the supine position with the arm abducted. An anesthesiologist skilled with ultrasound guided regional anesthesia placed the ultrasound probe at the midclavicular level inferolaterally to locate the axillary artery and vein, and then moved laterally until the lower border of the pectoralis minor is identified at the level of the third or fourth rib. Needle advanced in the plane mode until the tip enter

Thirty minutes prior induction of general anesthesia, Axillary Infiltration group: Patient in the supine position with the arm abducted. An anesthesiologist skilled with ultrasound guided regional anesthesia placed the ultrasound probe at the midclavicular level inferolaterally to locate the axillary artery and vein, and then moved laterally until the lower border of the pectoralis minor is identified at the level of the third or fourth rib. Needle advanced in the plane mode until the tip entered the area below the pectoralis half distance between the axillary vein and the rib and 20.5 ml of ropivacaine 0.5% was injected. The anesthesiologist is able to be sure that the quantity injected under ultrasound is in the fatty area of the axilla.

Sponsors

Maroun B, Ghabach
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

1. ASA grade I–II 2. Female patients 3. Breast Surgery 4. Fasting overnight 5. Informed consent

Exclusion criteria

1. Infection at the block site 2. Coagulopathy 3. Morbid obesity (BMI >40 kg m-2) 4. Allergy to local anesthetics 5. Decreased pulmonary reserve 6. Major cardiac disorders 7. Renal dysfunction 8. Pre-existing neurological de?cits 9. Psychiatric illness

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026