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Prophylactic anticoagulant use in weight loss surgical patients

Prophylactic enoxaparin use and outcomes in obese patients undergoing laparoscopic adjustable gastric band surgery

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12619000907145
Enrollment
212
Registered
2019-06-27
Start date
2018-06-01
Completion date
2018-12-31
Last updated
2019-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The hypothesis (based of the previous literature) of the study that obese patients should receive higher prophylactic anticoagulant doses. Therfore, the purpose of the study was to evaluate drug dosing practice of prophylactic anticoagulants in obese patients who underwent gastric band surgery and to look at the clinical outcomes (venous thromboembolism and major bleed). .

Interventions

No intervention was done. Drug dosing practice of enoxaparin and outcomes (venous thromboembolism and major bleed) were accessed in Laparoscopic adjustable gastric band patients. Patients were followed-up retrospectively from digital medical record for 90 days to observe any venous thromboembolism and major bleed incidence. There were 2 cases venous thromboembolism identified. Data was collected from year 2013-2017

Sponsors

Dr Syed Tabish Razi Zaidi
Lead SponsorIndividual

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

A retrospective cohort study was conducted of adult (age greater than or equal to 18 years) obese patients (BMI more than or equal to 30 kg/m2) who underwent primary and revisional bariatric surgery at the Royal Hobart Hospital (RHH) and the Hobart Private Hospital (HPH), from 1 Jan 2013 to 31 Dec 2017

Exclusion criteria

Patients were excluded from the study if they were on regular anticoagulant or vitamin K therapy, underwent a concurrent surgical procedure (e.g. hysterectomy), or had an established congenital or acquired bleeding disorder, varicose veins, renal impairment with an estimated glomerular filtration rate < 60 mL/min/1.73m2, prior heparin-induced thrombocytopaenia, haemorrhagic stroke within the previous 3 months, other surgery within the previous 3 months, or if relevant information was missing.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026