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The effect of weight stigma and the polycystic ovary syndrome (PCOS) disease label and causal explanations on intention to eat healthier and perceived personal control over weight: A randomised online study in reproductive aged women

The effect of weight stigma and the polycystic ovary syndrome (PCOS) disease label and causal explanations on intention to eat healthier and perceived personal control over weight: A randomised online study in reproductive aged women

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12619000906156
Enrollment
545
Registered
2019-06-27
Start date
2019-06-27
Completion date
2019-07-18
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

It is unknown whether knowing a diagnosis of PCOS encourages women to engage in recommended preventative activities for associated long-term implications, such as a healthy diet and exercise, and if this is more effective than giving advice regarding weight gain on its own. If genetic explanations for PCOS reduce personal agency/self-control and induce doubt about the effectiveness of non-biomedical treatments (lifestyle), this could have significant negative consequences. It is vital the potential impact of a PCOS diagnosis on lifestyle behaviours is explored. The aim of this study are threefold: - What is the effect of the PCOS label on intention to eat healthier compared to a weight label? - How does the PCOS label influence perceived personal control of weight compared to a weight label? - Does this differ depending on whether an environmental or genetic explanation is given?

Interventions

The intervention at Time 1 will be delivered as a hypothetical scenario online using Qualtrics survey software and will take approximately 15-20 minutes to complete. Intervention materials: A hypothetical scenario of a doctor's visit - female, reproductive aged participants will be asked to imagine they have been putting on weight easily and finding it hard to lose it, having irregular periods and more pimples than usual, and they go to their doctor to see if there is anything to be concerned a

The intervention at Time 1 will be delivered as a hypothetical scenario online using Qualtrics survey software and will take approximately 15-20 minutes to complete. Intervention materials: A hypothetical scenario of a doctor's visit - female, reproductive aged participants will be asked to imagine they have been putting on weight easily and finding it hard to lose it, having irregular periods and more pimples than usual, and they go to their doctor to see if there is anything to be concerned about. The first independent variable is label given ("you are experiencing these symptoms because you have PCOS" vs. "you are experiencing these symptoms because of your weight") and the second independent variable is the explanation given ("genes (DNA) play a major role" vs. "diet and other health behaviours play a major role") Participants will be randomised to receive one of four hypothetical scenarios. 1) PCOS label + genetic explanation 2) Weight label + genetic explanation 3) PCOS label + environmental explanation 4) Weight label + environmental explanation The full intervention reads: Imagine that for the past year you have been putting on weight easily and finding it hard to lose it. You have also noticed that your periods have become quite irregular and you have had more pimples than usual. You visit your general practitioner (GP) to see if there is anything to be concerned about. Your GP asks about your symptoms, measures your height and weight, and says… “I think you are experiencing these symptoms because [of your weight/you have Polycystic Ovary Syndrome (PCOS)].” -1st IV “This is likely due to a mix of factors. However, we now know from recent research that [genes (DNA)/diet and other health behaviours] -2nd IV- play a major role.” Your GP further explains… “[Being above your healthy weight range/Having PCOS] increases your risk of high blood pressure, reduced fertility and type II diabetes. You ask your GP what you should do. “Well… guidelines recommend making healthy lifestyle changes to try to lose weight and reduce these risks.” “I would suggest the first step is to focus on your diet to try to lose weight. This includes eating more fruit and vegetables and less foods high in sugar and saturated fats. For example, less sugary drinks, cakes and pastries, cereals, fatty meat and cream.” “If this doesn’t work, we can then try a medication to help you lose weight. But first, focus on your diet”

Sponsors

School of Public Health, University of Sydney
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Factorial
Primary purpose
Educational / counselling / training
Masking
Blinded (masking used) (Subject, Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

Participants will be Australian women aged 18-45 years with an adequate understanding of English and currently living in Australia.

Exclusion criteria

n/a

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026