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An investigation of different interventions designed to maintain the benefits following a group-based memory rehabilitation program in stroke patients.

Enhancing the effects of post-stroke memory rehabilitation: A feasibility trial of two e-Health interventions to sustain the benefits of a memory skills group.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12619000823178
Acronym
Memory-SuSTAIN (Memory Strategy Skills Training Applied IN the long term)
Enrollment
38
Registered
2019-06-07
Start date
2019-12-16
Completion date
2021-02-25
Last updated
2026-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Addressing memory problems after stroke is a research priority due to significant unmet needs reported by survivors of stroke. Memory rehabilitation, including group programs based on teaching people strategies to compensate for their memory problems (such as using diaries or calendars), has been shown to produce significant short-term improvements in memory after a stroke. However, difficulties establishing new strategies into everyday routines can mean that effects are inconsistently maintained over time. In this project, we seek to evaluate the following two eHealth maintenance intervention programs that are designed to sustain the improvements in everyday memory made following six weeks of group-based memory skills training: 1) Booster sessions delivered via telehealth (videoconferencing), and 2) SMS or email reminders prompting use of memory strategies taught. As well as evaluating whether these eHealth interventions are effective in maintaining the use of strategies that enhance memory function, we are seeking to assess whether these interventions are appropriate, practical, and potentially cost-effective. In order to evaluate whether these intervention strategies are effective in helping people maintain their benefits, we will compare the results that we find from the two treatment options against results from having no maintenance support (which is the current practice). Identifying effective strategies for maintaining the benefits of memory rehabilitation could help reduce the long-term impact of these problems after a stroke. These benefits could include increased independence and employment opportunities, as well as better quality of life for those recovering from a stroke and their families.

Interventions

Prior to commencing in the trial, participants will have completed a six-week memory skills group program. The group program comprises one two-hour session each week (including breaks) in groups of 3-8 people who report memory difficulties after experiencing an acquired brain injury (ABI). Sessions are facilitated in-person by qualified clinicians. Program content includes psychoeducation regarding memory functioning, practical training in internal and external compensatory memory strategies, an

Prior to commencing in the trial, participants will have completed a six-week memory skills group program. The group program comprises one two-hour session each week (including breaks) in groups of 3-8 people who report memory difficulties after experiencing an acquired brain injury (ABI). Sessions are facilitated in-person by qualified clinicians. Program content includes psychoeducation regarding memory functioning, practical training in internal and external compensatory memory strategies, and information about relevant impacts to memory functioning from lifestyle factors such as diet, sleep, and exercise. Interactive in-session exercises and between-session homework tasks are included to encourage practice and application of trained skills and strategies in everyday contexts. All memory skills group sessions will be video recorded throughout the study period, for treatment fidelity checks of a random selection of sessions by an independent expert. Treatment fidelity monitoring will include measures of adherence (using a session content checklist) and competence (using the eNACT Group Facilitation Competency Checklist). At the conclusion of the memory group program, interested participants will be contacted by study staff to be formally enrolled in the Memory-SuSTAIN study and randomised into one of the following two study arms (or a control condition, consisting of usual care involving no active follow-up maintenance): Arm 1: Telehealth booster sessions Participants in the Booster Sessions condition will receive three fortnightly sessions of one-hour duration each, with a trained clinician. Sessions will comprise: • Checking the progress of rehabilitation goals (previously negotiated with memory group clinicians); • Reviewing and consolidating key compensatory and lifestyle strategies covered during the memory group program; • Expanding the number and range of everyday situations to which these memory strategies could be applied; and • Addressing any barriers to ongoing implementation of strategies. Booster sessions will occur remotely via videoconferencing using Zoom, a freely available software program facilitating Internet-enabled videoconferencing. Booster sessions will also be video recorded and treatment fidelity checks conducted by an independent expert. Arm 2: SMS/Email Reminders Participants in the SMS/Email Reminder condition will receive one strategy message per week for six weeks, sent either to their mobile phone as a text message or to a nominated email address, depending on each participant’s preference. Reminder messages will prompt participants to use their three most relevant strategies learned during the memory group program. Following group allocation, participants in the SMS/Email Reminders condition will be asked to nominate their three most useful personally salient strategies from a list of all strategies taught in the memory skills group. These strategies will inform the range of reminder prompts that they receive. Strategies will be identified from a list covering the following areas: Internal Strategies: o Using repetition to enhance encoding (mental rehearsal, asking others to repeat, re-reading text); o Using association to enhance retrieval; o Route-finding strategies: Paying attention to key features to enhance encoding; o Using context to assist recall; o Word-finding and conversations: focusing on meaning, using association, and descriptions; o Learning and recalling names: using alphabet search, association, and elaboration; External Strategies: o Optimising the home environment: decreasing distractions, reducing clutter; o Using note-taking, diaries, calendars, physical reminders, and alarms; o Using smartphones and electronic devices; o Using checklists for complex tasks. Messages will be delivered using the iVERVE platform, an electronic automated messaging system designed and developed by Cadilhac et al. (2018) for message-based e-health interventions. iVERVE will store a bank of strategy reminder messages and securely extract de-identified participant data (selected strategies matched with each relevant participant’s nominated phone number or email address) from a secure web-based database management system (REDCap; Harris et al., 2009). Study data will be collected and managed using REDCap (Research Electronic Data Capture) electronic data capture tools hosted and managed by Helix (Monash University; Harris et al., 2009). REDCap is a secure, web-based application designed to support data capture for research studies, providing 1) an intuitive interface for validated data entry; 2) audit trails for tracking data manipulation and export procedures; 3) automated export procedures for seamless data downloads to common statistical packages; and 4) procedures for importing data from external sources. Automated messages will be sent to participants at designated times, once per week for six weeks.

Sponsors

La Trobe University
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Participants will satisfy the following criteria: 1. Adults (age at least 18 years); 2. Primary diagnosis of stroke as determined by medical records; 3. At least 3 months post-stroke; 4. Everyday memory complaints, reported by self or other; 5. Sufficient cognitive and English language skills to participate in a memory skills group; 6. Completion of a memory skills group program at any of the participating clinical sites (defined as attending at least 4 of the 6 memory group sessions); 7. Access to a computer with a webcam and internet connection; and 8. Access to either SMS text messaging via a mobile phone with active service, or an active email service.

Exclusion criteria

1. Severe psychiatric illness 2. Known presence of a neurodegenerative conditions (e.g. dementia), severe mental health conditions, or other known neurological disorder impacting cognition 3. Major illness and unlikely to survive up to final follow-up assessment 4. Current participation in other individual rehabilitation sessions focusing on memory or other cognitive functions.

Outcome results

None listed

Source: ANZCTR · Data processed: Apr 23, 2026