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Evaluating the effectiveness of chest physiotherapy treatment using lung ultrasound in an intensive care population

Diagnostic lung ultrasound in critical care: lung aeration changes associated with chest physiotherapy treatment

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12619000783123
Acronym
DUCHESS
Enrollment
43
Registered
2019-05-27
Start date
2019-08-27
Completion date
2021-09-14
Last updated
2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Diagnostic lung ultrasound will be used to diagnose acute lobar atelectasis in a mechanically ventilated population in intensive care. Lung ultrasound scans will also allow the research physiotherapist to assign aeration scores pre and post delivery of chest physiotherapy treatment. We hypothesise that lung ultrasound will be able to detect changes in lung aeration associated with a single chest physiotherapy treatment. This single centre prospective cohort trial of 43 mechanically ventilated patients will be conducted in intensive care at Royal North Shore Hospital.

Interventions

Lung ultrasound examinations, as an adjunct to standard clinical assessment, will be performed on mechanically ventilated patient’s pre and post standard care chest physiotherapy treatment during a single clinical physiotherapy session in the ICU stay. LU will be conducted by the research physiotherapist, Louise Hansell. The patient will be imaged in the semi-recumbent, 30-45 degree head-up, position. Lung ultrasound will be used to determine aeration patterns prior to delivery of physiotherapy

Lung ultrasound examinations, as an adjunct to standard clinical assessment, will be performed on mechanically ventilated patient’s pre and post standard care chest physiotherapy treatment during a single clinical physiotherapy session in the ICU stay. LU will be conducted by the research physiotherapist, Louise Hansell. The patient will be imaged in the semi-recumbent, 30-45 degree head-up, position. Lung ultrasound will be used to determine aeration patterns prior to delivery of physiotherapy treatment, and again following treatment, with a lung ultrasound score and lung reaeration score assigned to demonstrate the amount of focal and global aeration change. It is estimated that each lung ultrasound will take between 15-30 minutes. Lung auscultation and chest radiographs obtained from conventional respiratory bedside assessment as well as physiological measures (including arterial blood gas data, peripheral oxygen saturations, respiratory rate, tidal volume, pressure support and positive end expiratory pressure values as appropriate, PaO2/FiO2 ratio and static lung compliance (tidal volume on driving pressure) if in mandatory ventilation mode) will also be used to determine aeration change. Standard care chest physiotherapy for ventilated patients will vary between patients depending on the location of atelectasis and the clinical decision made by the clinical physiotherapist. Treatment typically comprises of positioning, mobilisation, manual/ventilator hyperinflation, Percussions/vibrations/shakes, suctioning or augmented cough, or a combination of any of these techniques. For all patients who have undergone LU, results of thoracic CT scans performed for clinical purposes (if available) within 12hrs of having LU will also be collected. Presence or absence of acute lobar atelectasis on LU, chest radiograph and CT will be recorded.

Sponsors

The University of Sydney
Lead SponsorUniversity

Study design

Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Diagnosis
Masking
Blinded (masking used) (Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

- Patients over 18 years of age - Hospitalised in intensive care - Mechanical ventilation expected for greater than 24 hours - Suspicion of acute lobar atelectasis identified by the treating intensive care team - Arterial line in place - No previous chest physiotherapy treatment for their current episode of acute lobar atelectasis - Chest x-ray (CXR) available within 12 hours of physiotherapy assessment - Willingness of next of kin to give written consent and comply with the study

Exclusion criteria

- Presence of a contraindication to chest physiotherapy - Absence of a chest x-ray or a chest x-ray taken greater than 12 hours from the time of physiotherapy assessment - Physiotherapist qualified in LU not available - LU not possible (subcutaneous emphysema dressings, drains, oedema etc.) - Body habitus preventing optimal imaging, BMI >40 - Refusal from the patient’s next of kin to participate in the study - Withdrawal/limitations of medical care with impending death

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 12, 2026