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Impact of patient position and intraabdominal gas used in laparoscopic hysterectomy on optic nerve sheath diameter which reflects intracranial pressure

Impact of pneumoperitoneum and patient position on optic nerve sheath diameter in laparoscopic hysterectomies.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12619000674134
Enrollment
38
Registered
2019-05-06
Start date
2019-03-15
Completion date
2019-05-10
Last updated
2019-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

We hypothesized that pneumoperitoneum and Trendelenburg position applied during laparoscopic hysterectomy would impact intracranial pressure. Optic nerve sheath diameter measured with USG reflects intracranial pressure. Therefore we are enrolling patients undergoing a laparoscopic hysterectomy in our institute and measuring optic nerve sheath diameter with a linear 13-6 megahertz probe during different stages of the surgery (eg. before and after pneumoperitoneum, before and after Trendelenburg position). The primary outcome is the change in optic nerve sheath diameter with pneumoperitoneum and Trendelenburg position. The secondary outcome is postoperative nausea and vomiting and postoperative headache.

Interventions

Optic nerve sheath diameter (ONSD) will be measured at six times using ultrasound : 1. Before anesthesia 2. 10 minutes after pneumoperitoneum 3. 10 minutes after Trendelenburg position 4. 60 minutes after Trendelenburg position 5. 10 minutes after supine position 6.20 minutes after CO2 desufflation A laparoscopic hysterectomy will be carried out by the same surgeon who has over 10 years experience in gynecologic laparoscopy Anesthesia will be managed by the same anesthesiologists with 9 years

Optic nerve sheath diameter (ONSD) will be measured at six times using ultrasound : 1. Before anesthesia 2. 10 minutes after pneumoperitoneum 3. 10 minutes after Trendelenburg position 4. 60 minutes after Trendelenburg position 5. 10 minutes after supine position 6.20 minutes after CO2 desufflation A laparoscopic hysterectomy will be carried out by the same surgeon who has over 10 years experience in gynecologic laparoscopy Anesthesia will be managed by the same anesthesiologists with 9 years experience ONSD measurement will be performed by a 15-year experienced radiologist.

Sponsors

University of Health Sciences
Lead SponsorUniversity

Study design

Allocation
Non-randomised trial
Primary purpose
Diagnosis

Eligibility

Sex/Gender
All
Age
38 Years to 78 Years
Healthy volunteers
No

Inclusion criteria

Female patients undergoing laparoscopic hysterectomy

Exclusion criteria

Patients with previous history of ocular disease, ocular surgery, neurologic disease and transient ischemic attack,

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026