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An integrated public health strategy to manage chronic respiratory disease and reduce smoking in Vietnam: a pilot study

An integrated public health strategy to manage chronic respiratory disease and reduce smoking in Vietnam: a pilot study

Status
Completed
Phases
Phase 4
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12619000554167
Acronym
The VCAPS3 Study
Enrollment
536
Registered
2019-04-09
Start date
2019-03-27
Completion date
2020-01-16
Last updated
2021-10-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This is a pilot study aims to assess the feasibility of an integrated public sector intervention that is hypothesised to (a) reduce the number of exacerbations among individuals with chronic respiratory disease presenting to healthcare facilities and (b) reduce the proportion of current smokers among patients presenting to healthcare facilities and healthcare workers in the facilities. Three interventions will be implemented, including (a) chronic respiratory disease intervention, (b) patient smoking cessation intervention, and (c) health facility smoking cessation intervention. This study will be conducted in three government district health facilities in rural districts of Hanoi Capital, Vietnam. Participants will be followed for 12 months.

Interventions

There are three interventions 1. Chronic respiratory disease intervention A syndromic approach to diagnosis and treatment for patients with COPD/asthma. The treatment algorithm consists of three steps. Step 1 treatment uses as-needed budesonide/formoterol (160/4.5ug per dose) inhalation for relieving day-to-day respiratory symptoms. Step 2 includes twice daily and as-needed budesonide/formoterol (160/4.5ug per dose) inhalation. Patients who require step 3 treatment will be referred to a higher l

There are three interventions 1. Chronic respiratory disease intervention A syndromic approach to diagnosis and treatment for patients with COPD/asthma. The treatment algorithm consists of three steps. Step 1 treatment uses as-needed budesonide/formoterol (160/4.5ug per dose) inhalation for relieving day-to-day respiratory symptoms. Step 2 includes twice daily and as-needed budesonide/formoterol (160/4.5ug per dose) inhalation. Patients who require step 3 treatment will be referred to a higher level health facility for respiratory specialist evaluation. Treatment will be stepped up when a patient is not under good symptom control or had an exacerbation, providing that the patient uses the inhaler treatment correctly. After recruitment, all patients start with step 1 treatment. At 4 weeks, patients will return to the clinic for evaluation and decision on the treatment step. When returning for clinical assessment, patients are asked to bring back inhalers for evaluating treatment adherence and inhaler technique. The treating physician will also decide the time for the next clinical evaluation, when the decision on treatment step will take place again. All recruited patients will follow the treatment algorithm for one year. The decision on staying in the same step, stepping up or down, is determined by treating physician based on the patient's symptom control, exacerbation, adherence to suggested treatment, and inhaler technique. For example, a patient under treatment step 1 had an exacerbation 2 weeks before this visit. The patient has a good inhaler technique and has been following the treatment step 1, evaluated by the treating physician. The physician should step up to treatment from step 1 to step 2. 2. Health facility smoking cessation intervention Implementation of smoke-free hospital policy Hospital leaders are responsible for formulating rules and implementing smoke-free hospital policy, with assistance from research staff. Smoke-free hospital policy includes the prohibition of smoking and selling tobacco products on the hospital premises. The regulations will be announced and all members in the hospital should follow, including patients and visitors. Training for healthcare workers to provide brief advice on smoking cessation A one-off 2-hour smoking cessation workshop will be held by research staff to train healthcare workers on brief intervention to patients. The workshop will include a lecture and practice of brief intervention using 5A's approach. Healthcare workers who are smokers are encouraged to quit. After commencing the intervention, research staff will conduct regular visits to monitor the implementation. Issues identified will be raised and discussed with hospital leaders. 3. Patient smoking cessation intervention Smoking cessation brief advice provided by healthcare workers at district facilities. After the above-mentioned smoking cessation workshop, healthcare workers at the outpatient clinic, emergency department, and inpatient department will ask patients about smoking behaviour. For patients who are current smokers, healthcare workers will advise them to quit and invite them to join a follow-up smoking cessation programme. Follow-up smoking cessation programme Smokers who consent to join the programme will receive follow-up quitline counselling for 9 times (1 day, 1 week, 2 weeks, 3 weeks, 4 weeks, 3 months, 6 months, 9 months, and 12 months after recruitment). Participants can also call the quitline if they need extra support. The follow-up programme also contains text messages to help participants quit smoking. The text message service is integrated with quitline counselling. The service lasts for 3 months, starting with one text per day and decreasing over time.

Sponsors

Woolcock Institute of Medical Research
Lead SponsorOther

Study design

Allocation
Non-randomised trial
Primary purpose
Treatment

Eligibility

Sex/Gender
All
Age
12 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Chronic respiratory disease intervention (a) Aged 12 years and over presenting to district health facilities, AND (b) At least one of cough, dyspnea, wheeze, or chest tightness, AND (c) A history of at least one prior episode of respiratory symptoms that has required attendance at a health care facility within the past two years, AND (d) Demonstrated airflow limitation, defined as a pre-bronchodilator FEV1/FVC ratio less than 70% on spirometry or a peak flow meter reading less than 80% of predicted peak expiratory flow rate. OR (e) Probable asthma: answering yes to at least three of the nine questions in the respiratory symptom questionnaire. Smoking cessation intervention (a) Aged 12 years and over presenting to district health facilities, AND (b) Has smoked 100 cigarettes in his or her lifetime, AND (c) Currently smokes cigarettes

Exclusion criteria

Chronic respiratory disease intervention (a) Patients who are allergic to budesonide or formoterol (b) Pregnant women

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 12, 2026