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Understanding mechanism of progression of short-sightedness using progressive addition lenses

Impact of progressive addition lens spectacles on accommodation errors in young adults with short-sightedness

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12619000538145
Enrollment
56
Registered
2019-04-04
Start date
2019-04-10
Completion date
2020-07-16
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Myopia (short-sightedness) is the most common vision problem in children. Higher amounts are associated with vision threatening diseases in later life. Progressive addition spectacle lens designs, used primarily in presbyopia, appear to slow down the development of juvenile myopia but their efficacy tends to weaken after a period of about 12 months. The aim of this project is to further the understanding of the accommodation system (the near focusing mechanism) and drivers of the progression of myopia to ultimately lead to more effective lens designs. This study will improve understanding of eye structure changes during accommodation and provide a fundamental investigation of accommodation mechanisms in myopia. It will potentially contribute to improved designs and use of lenses for the treatment of myopia in children.

Interventions

Short-sighted participants will be recruited from Queensland University of Technology and they will be provided with progressive addition lens spectacles to wear during waking hours. Progressive addition lenses contain a corridor of increasing power between distance and near zones, and are used to slow the worsening of myopia in children and young adults. Two designs of the progressive addition lenses will be used. Type 1 is a conventional lens design with a wide corridor and type 2 is an interv

Short-sighted participants will be recruited from Queensland University of Technology and they will be provided with progressive addition lens spectacles to wear during waking hours. Progressive addition lenses contain a corridor of increasing power between distance and near zones, and are used to slow the worsening of myopia in children and young adults. Two designs of the progressive addition lenses will be used. Type 1 is a conventional lens design with a wide corridor and type 2 is an interventional design with a narrow corridor. Participants will be followed up every three months for 12 months to measure the focussing error. The principal investigator (PI), who is an optometrist, will perform refraction to check the power of the spectacles under supervision of A/Prof Katrina Schmid and Prof David Atchison in the Myopia Lab at the Queensland University of Technology. Then, the dispenser at the QUT optometry clinic verifies the segment heights measurements of the PI before ordering the spectacles. The participants will be asked to wear the spectacle during usual waking hours. The prescription of spectacles for distance will be between -1.0 and -6.0 dioptre with the addition power of 1.50 D. The focussing errors of the participants will be measured with the new spectacles at 0, 3, 6, 9 and 12 months timeline from the commencement of the intervention. When the spectacles arrived from the lab, the prescription will be verified and the vision at far and near will be checked. After spectacles are provided, the participants will be contacted via text or phone in a week to check the adaptation with the spectacles and duration of the spectacles wear. The participant will be contacted again after a month to assess the adaptation and duration of wearing hours.

Sponsors

A/Prof Katrina L Schmid
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to 27 Years
Healthy volunteers
No

Inclusion criteria

Short-sightedness

Exclusion criteria

Person with other eye conditions such as glaucoma. Spectacles power more than - 6.0 dioptre. Anisometropia or astigmatism of more than 1.5 dioptre

Outcome results

None listed

Source: ANZCTR · Data processed: Aug 9, 2026