None listed
Conditions
Brief summary
Obesity is counted as one of civilization’s most significant diseases. It is a serious 21st century problem in both middle and highly developed countries, and the percentage of people struggling with excess weight is on the increase. Nutritionists and doctors alike are raising the alarm because this phenomenon affects both adults and children. This is exceptionally worrying for society at large. Therefore, research on adipose tissue activity has gained a new dimension and is fast becoming a crucial area of research for human health. Studies from recent years prove that adipose tissue does not only control homeostasis but also has endocrine functions. The excessive adipose tissue results in an increase in the volume of adipocytes, which is the result of the impaired adipokine secretion. What is also typical, is the disrupted lipid homeostasis and thus a greater susceptibility to metabolic and cardiovascular diseases. Increasingly, the systemic cryostimulation is perceived as one of the potential methods which can affect both the pace of the metabolic rate and the series of biochemical reactions which occur in the adipose tissue. The available scientific sources do not provide unambiguous answers to the questions related to the impact of systemic cryostimulation on the adipokine secretion profile, especially among obese people. The aim of the study was to assess the effect of 20 systemic cryostimulation on: the profile of selected adipokines secreted in front of the adipose tissue, the concentration of C-reactive protein, and also haematological blood and lipid profile parameters among, both young obese men and men with normal body mass.
Interventions
The influence of the whole body cryostimulation on metabolites of adipose tissue, lipid profile and hematological parameters of blood in obese men and normal adipose tissue.
The aim of the study was to assess the effect of systemic cryostimulation on: the profile of selected adipokines secreted in front of the adipose tissue (adipokine, leptin, tumor necrosis factor alfa), the concentration of C-reactive protein, and also haematological blood and lipid profile parameters among, both young o
The influence of the whole body cryostimulation on metabolites of adipose tissue, lipid profile and hematological parameters of blood in obese men and normal adipose tissue. The aim of the study was to assess the effect of systemic cryostimulation on: the profile of selected adipokines secreted in front of the adipose tissue (adipokine, leptin, tumor necrosis factor alfa), the concentration of C-reactive protein, and also haematological blood and lipid profile parameters among, both young obese men and men with normal body mass. Study group was divided into obese and non-obese subjects, depending on the percentage of body fat: obese more than 26% body fat and non-obese men 8-21% body fat. All participants were subjected to 20 sessions of systemic cryostimulation (1 treatment per day, from Monday to Friday, excluding public holidays). The research was carried out at -120 ° C for 2-3 minutes in a cryochamber located in the Malopolskie Centrum Krioterapii in Cracow (the Malopolska Cryotherapy Centre at Al. Pokoju 82 in Cracow). Each cryostimulation treatment was preceded with a 30-second period of adaptation in the vestibule at -60 ° C. In addition, the first treatment in the cryochamber lasted 1.5 minutes, the second - 2 minutes, and the third and each subsequent - 3 minutes. The sessions in the low-temperature chamber were held in the afternoon, with the participation of a physician from the Cryotherapy Center, and the stay in the cryochamber was supervised by a suitably trained employee of the Cryotherapy Centre. The anthropometric measurements were taken from all patients before first and after last the treatment. The concentrations of selected adipokines and inflammation markers, and as well as haematological blood indicators along with the lipid profile were checked before and after the 10th and 20th cryostimulation.
Sponsors
The Bronislaw Czech Academy of Physical Education in Cracow
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
Male
Age
20 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
age 20-35, males, no contraindications to whole body cryostimulation, medical qualification, normal (8-21%) or increased (>26%) percentage of adipose tissue determined for age and sex
Exclusion criteria
cancer, advanced cardio-respiratory diseases, cardiac arrhythmias, previous blocked arteries, hypertension (>160/100 mmHg), transient ischaemic attacks, improper operation of the thyroid, diabetes, cold intolerance, frostbite, skin damage, kidney, liver or bladder disease, stroke, claustrophobia, smoking, total cholesterol (>300 mg/dL), weight-reducing diet, taking anti-inflammatory drugs.
Outcome results
None listed