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A retrospective cohort study to evaluate outcomes in carotid endartertomy vs carotid artery stenting in carotid artery disease

A retrospective cohort study to evaluate outcomes in carotid endartertomy vs carotid artery stenting in carotid artery disease

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12619000516189
Enrollment
350
Registered
2019-04-01
Start date
2019-05-01
Completion date
2019-08-31
Last updated
2019-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Stroke is the most common life threatening and debilitating neurological disorder. It is commonly caused by the flicking off of plaque from calcified arteries in the neck region in patients with atherosclerotic internal carotid artery stenosis. This study retrospectively compares the outcomes after 2 different treatment options for carotid artery stenosis: carotid artery stenting (CAS) and carotid endarterecromy (CEA). All patients who underwent either procedure performed by the primary surgeon, in 4 locations will be included. Specific outcome measures are: (1) post procedure occurrence of further clots in the arteries supplying the brain and (2) post procedure occurrence of external carotid (a branch of the artery being operated on) occlusion. In order to measure these outcomes, we will compare the clinical examination findings as well as imaging (MRI, ultrasound, CT angiography) results pre and post operatively. As CEA is currently the gold standard for treating this condition, we predict that long term outcomes are better in CEA as compared to CAS.

Interventions

Carotid Endarterectomy Patients observed in this study are those with unilateral and or bilateral carotid artery stenosis and/or occlusion. They underwent either Carotid endarterectomy or Carotid artery stenting, performed by one primary surgeon. The decision to offer carotid endarterectomy vs carotid artery stenting was based on the surgeons clinical assessment of the patient. All patients recruited will have had their procedures performed at Hollywood Private Hospital, Nedlands, WA or Royal

Carotid Endarterectomy Patients observed in this study are those with unilateral and or bilateral carotid artery stenosis and/or occlusion. They underwent either Carotid endarterectomy or Carotid artery stenting, performed by one primary surgeon. The decision to offer carotid endarterectomy vs carotid artery stenting was based on the surgeons clinical assessment of the patient. All patients recruited will have had their procedures performed at Hollywood Private Hospital, Nedlands, WA or Royal Perth Hospital, Perth, WA between the years 2006 and 2018. All patients have been followed at 3 and 6 months with imaging and in person at 1 year post op by the same primary surgeon in his rooms.

Sponsors

Dr Kishore Siuenarine
Lead SponsorIndividual

Eligibility

Sex/Gender
All
Age
40 Years to No maximum
Healthy volunteers
No

Inclusion criteria

All patients who underwent either Carotid artery stenting or Carotid endarterectomy performed by one vascular surgeon between the years 2006 and 2018 are included

Exclusion criteria

Exclusion criteria included allergy to heparin, aspirin or clopidogrel, contraindication to MRI, intracranial hemorrhage, dementia or neurologic illness that might confound neurological evaluation.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026