An observational study investigating and auditing the safety, tolerability and further efficacy characteristics of a pharmaceutical grade cannabis medicine (NanaBis™) prescribed to eligible patients for the management of cancer related or non-cancer related pain in general and specialty medical practices.

This is an observational, multicentre study conducted in Australia with patients who are about to start a therapy with NanaBis™ for the management of cancer related or non-cancer related pain. Patients are to be enrolled into the study no earlier than the Consenting Doctor’s decision to initiate treatment with NanaBis™. It is mandatory that the prescriber’s decision to start treatment with NanaBis™ was taken independently and before the decision to give the patient the option to participate in the study. Consenting Doctors' clinics will be asked to progressively enrol eligible patients until the maximum inclusion threshold is reached. Participants will be followed monthly for a maximum of 12 months from the signing of the informed consent or until death, withdrawal of consent, loss of follow-up/record, whichever comes first. During the follow-up visits (which will take approximately 15-20 minutes) assessments will be performed according to routine local clinical practice. De-identified data collected at each visit and reported to the Sponsor must include the information listed under ‘Study Procedures’. Follow-up de-identified patient reports detailing the required information will be sent to the Sponsor for a maximum of 12 months (Reports to coincide with patient visit for follow-up consultation and/or new NanaBis™ prescription).