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An investigation of blood clots and other complications related to longer peripheral intravenous catheters in children

Thrombotic complications to paediatric midline catheters

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12619000472178
Enrollment
100
Registered
2019-03-21
Start date
2019-05-13
Completion date
2021-06-23
Last updated
2023-02-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Midline catheters are being used more frequently in both the adult and paediatric population. However, data is sparse regarding midline-related complications in the paediatric setting. Our aim is to determine the frequency of venous thrombosis related to paediatric midline catheters. We will also investigate the frequency of other midline-related complications, and the average dwell-time for paediatric midline catheters. The need for additional venous access to complete the intended therapy will also be registered.

Interventions

The primary outcome of the study is the frequency of midline catheter-related venous thrombosis in children receiving midline catheters at Astrid Lindgrens Children´s Hospital. 100 children receiving midline catheters at Astrid Lindgrens Children´s Hospital will be included in the study. The objectives of the study is primary to characterize the frequency of midline catheter-related venous thrombosis but also other possible complications in children receiving midline catheters at Astrid Lindgre

The primary outcome of the study is the frequency of midline catheter-related venous thrombosis in children receiving midline catheters at Astrid Lindgrens Children´s Hospital. 100 children receiving midline catheters at Astrid Lindgrens Children´s Hospital will be included in the study. The objectives of the study is primary to characterize the frequency of midline catheter-related venous thrombosis but also other possible complications in children receiving midline catheters at Astrid Lindgren Children´s Hospital. Patients will be followed for clinical signs of midline-related venous thrombosis as long as the catheter is in place. Ultrasonography will be used to detect asymptomatic venous thrombosis at the time of midline catheter removal. Patients that develop midline-related venous thrombosis will be followed until the end of treatment. Patients will be followed for other midline-related complications, such as infection, thrombophlebitis and mechanical complications. Life-span of midline catheter and the need for additional venous access to complete therapy will also be recorded. The total duration of observation per participant will be approximately 1-2 weeks.

Sponsors

Department of Paediatric Perioperative Medicine and Intensive Care, Karolinska University Hospital
Lead SponsorHospital

Eligibility

Sex/Gender
All
Age
0 to 18 Years
Healthy volunteers
No

Inclusion criteria

All children receiving midline catheters at Astrid Lindgren Children´s hospital.

Exclusion criteria

Previous venous thrombosis in the cannulated vein

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026