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The effects of electrical stimulation treatment on adults with MS with swallowing problems

Effects of Neuromuscular Electrostimulation in the Treatment of Dysphagia in Adults with Multiple Sclerosis: A Randomized Controlled Trial

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12619000414112
Enrollment
12
Registered
2019-03-13
Start date
2016-11-15
Completion date
2018-10-30
Last updated
2019-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study will evaluate the effectiveness of electrical stimulation in improving swallowing function and quality of life among adults with MS with swallowing problems. Research around electrical stimulation suggests that there is considerable potential for participants of this project to improve their functional swallowing abilities and hence improving quality of life and emotional wellbeing.

Interventions

Neuromuscular electrical stimulation (NMES). There are two arms in this study: 1) Treatment group receiving active stimulation 2) Control group receiving sham stimulation Treatment group: - Received active NMES (11.5 mA; range 9–16.5 mA)) + swallowing exercise - Swallowed every 20 seconds, for a total of 60 swallows per session - Were stimulated for 20 minutes per session, for a total of two sessions per week, for three consecutive weeks. The treatment study took place at the Communication Di

Neuromuscular electrical stimulation (NMES). There are two arms in this study: 1) Treatment group receiving active stimulation 2) Control group receiving sham stimulation Treatment group: - Received active NMES (11.5 mA; range 9–16.5 mA)) + swallowing exercise - Swallowed every 20 seconds, for a total of 60 swallows per session - Were stimulated for 20 minutes per session, for a total of two sessions per week, for three consecutive weeks. The treatment study took place at the Communication Disorders Treatment and Research Clinic (CDTRC) at The University of Sydney. A speech pathologist (SLP) with 10 years’ experience contacted the participants in the treatment group and set a schedule for their treatment sessions. The SLP sent reminder text messages to the participants 2 days before the session. During the NMES treatment the SLP positioned two electrodes below the participant’s chin, specifically between the tip of the chin and the hyoid bone, in order to stimulate the floor of the mouth muscles. After placing the electrodes, the SLP set the stimulation. Participants in the treatment group were stimulated set just below the highest tolerable intensity to ensure muscle contraction, whereas in the control group participants were stimulated at a sensory level only, which did not elicit contraction of the targeted muscles. Participants in the treatment group, were instructed to swallow as hard as they could every time they felt the electric current, and to rest in between the cycles of stimulation. Participants in the control group were instructed to swallow as hard as they could every time they heard a beep sound from the NMES device, and to rest in between the cycles of stimulation. Thus, all participants had to swallow every 20 seconds, for a total of 60 swallows per session. Each participant was stimulated for 20 minutes per session, for a total of two sessions per week, for three consecutive weeks.

Sponsors

Hans Bogaardt
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Initial eligibility criteria for participants were adults above the age of 18 years, with a confirmed diagnosis of MS and a self/family report of swallowing difficulties. Further eligibility criteria were based on the presence of swallowing difficulties as shown in the FEES during the first session.

Exclusion criteria

Exclusion criteria were a history of dysphagia that was unrelated to MS, previous treatment with electrical stimulation, or if they did not meet any of the inclusion criteria..

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026